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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
5
hits in this display
Target
Arachidonate 5-lipoxygenase-activating protein
(Homo sapiens (Human))
TBA
Ligand
BDBM50152151
(CHEMBL3781006)
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Affinity Data
IC50: 7nM
Assay Description:
Inhibition of FLAP in human PMNL cells assessed as reduction in all-trans isomers of LTB4 and 5-HETE formation preincubated with enzyme for 15 mins f...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
PubMed
Copy BDB DOI
Target
Arachidonate 5-lipoxygenase-activating protein
(Homo sapiens (Human))
TBA
Ligand
BDBM50152151
(CHEMBL3781006)
Copy SMILES
Copy InChI
Affinity Data
IC50: 7nM
Assay Description:
Inhibition of FLAP in human monocyte assessed as reduction in all-trans isomers of LTB4 and 5-HETE formation preincubated with enzyme for 15 mins fol...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
PubMed
Copy BDB DOI
Target
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human))
University Of Campania "Luigi Vanvitelli
Curated by
ChEMBL
Ligand
BDBM50152151
(CHEMBL3781006)
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Affinity Data
IC50: 65nM
Assay Description:
Inhibition of 5-LOX (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Arachidonate 5-lipoxygenase-activating protein
(Homo sapiens (Human))
TBA
Ligand
BDBM50152151
(CHEMBL3781006)
Copy SMILES
Copy InChI
Affinity Data
IC50: 240nM
Assay Description:
Inhibition of FLAP in Ca+2 ionophore A23187 stimulated human neutrophils assessed as 5-LO product formation preincubated for 15 mins measured after 1...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human))
University Of Campania "Luigi Vanvitelli
Curated by
ChEMBL
Ligand
BDBM50152151
(CHEMBL3781006)
Copy SMILES
Copy InChI
Affinity Data
IC50: 8.00E+3nM
Assay Description:
Inhibition of recombinant human 5-LO expressed in Escherichia coli BL21 assessed as 5-LO product formation preincubated for 15 mins followed by addit...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI