Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 6 hits in this display   

TargetBeta-1 adrenergic receptor(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50328285(1-phenoxy-3-(1-(thieno[2,3-d]pyrimidin-4-yl)piperi...)
Affinity DataKi:  72nMAssay Description:Displacement of [125I]-cyanopindolol from human adrenergic beta-1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50328285(1-phenoxy-3-(1-(thieno[2,3-d]pyrimidin-4-yl)piperi...)
Affinity DataKi:  113nMAssay Description:Displacement of [125I]-cyanopindolol from human adrenergic beta3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50328285(1-phenoxy-3-(1-(thieno[2,3-d]pyrimidin-4-yl)piperi...)
Affinity DataKi:  189nMAssay Description:Displacement of [125I]-cyanopindolol from human adrenergic beta2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50328285(1-phenoxy-3-(1-(thieno[2,3-d]pyrimidin-4-yl)piperi...)
Affinity DataIC50:  862nMAssay Description:Antagonist activity at human recombinant adrenergic beta2 receptor expressed in CHO cells assessed as inhibition of isoproterenol-induced cyclic AMP ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1 adrenergic receptor(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50328285(1-phenoxy-3-(1-(thieno[2,3-d]pyrimidin-4-yl)piperi...)
Affinity DataEC50:  5nMAssay Description:Agonist activity at human recombinant adrenergic beta1 receptor expressed in CHO cells assessed as cyclic AMP formation by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50328285(1-phenoxy-3-(1-(thieno[2,3-d]pyrimidin-4-yl)piperi...)
Affinity DataEC50:  15nMAssay Description:Displacement of [125I]-cyanopindolol from human adrenergic beta3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed