Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 6 hits in this display   

TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50318990((1-(3-(9H-carbazol-4-yloxy)-2-hydroxypropyl)piperi...)
Affinity DataKi:  0.300nMAssay Description:Displacement of [125I]cyanopindolol from human adrenergic beta2 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1 adrenergic receptor(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50318990((1-(3-(9H-carbazol-4-yloxy)-2-hydroxypropyl)piperi...)
Affinity DataKi:  32nMAssay Description:Displacement of [125I]cyanopindolol from human adrenergic beta-1 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50318990((1-(3-(9H-carbazol-4-yloxy)-2-hydroxypropyl)piperi...)
Affinity DataKi:  250nMAssay Description:Antagonist activity at human adrenergic beta3 receptor expressed in CHOK1 cells assessed as inhibition of cAMP accumulation by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50318990((1-(3-(9H-carbazol-4-yloxy)-2-hydroxypropyl)piperi...)
Affinity DataIC50:  32nMAssay Description:Antagonist activity at human adrenergic beta2 receptor expressed in CHOK1 cells assessed as inhibition of cAMP accumulation by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50318990((1-(3-(9H-carbazol-4-yloxy)-2-hydroxypropyl)piperi...)
Affinity DataEC50:  385nMAssay Description:Agonist activity at human adrenergic beta3 receptor expressed in CHOK1 cells assessed as cAMP accumulation by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1 adrenergic receptor(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50318990((1-(3-(9H-carbazol-4-yloxy)-2-hydroxypropyl)piperi...)
Affinity DataEC50:  310nMAssay Description:Agonist activity at human adrenergic beta1 receptor expressed in CHOK1 cells assessed as cAMP accumulation by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed