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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetCaspase-1(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50171145((S)-2-(2-Chloro-phenyl)-8-oxo-5,6,7,8-tetrahydro-1...)
Affinity DataIC50:  14nMAssay Description:Inhibitory activity towards CASP1 using fluorogenic substrates following an incubation for over 30 min at 37 degree CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-8(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50171145((S)-2-(2-Chloro-phenyl)-8-oxo-5,6,7,8-tetrahydro-1...)
Affinity DataIC50:  336nMAssay Description:Inhibitory activity towards CASP8 using fluorogenic substrates following an incubation for over 30 min at 37 degree CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50171145((S)-2-(2-Chloro-phenyl)-8-oxo-5,6,7,8-tetrahydro-1...)
Affinity DataIC50:  1.84E+3nMAssay Description:Inhibitory activity towards CASP3 using fluorogenic substrates following an incubation for over 30 min at 37 degree CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed