Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 24 hits in this display   

TargetTGF-beta receptor type-1(Homo sapiens (Human))
Medivation Technologies

US Patent
LigandPNGBDBM280367(4-{[2-(5-chloro-2-fluorophenyl)-5-(pyrrolidin-1-yl...)
Affinity DataIC50:  78.8nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ3 family of Ser/Thr kinases. The kinases ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Medivation Technologies

US Patent
LigandPNGBDBM280367(4-{[2-(5-chloro-2-fluorophenyl)-5-(pyrrolidin-1-yl...)
Affinity DataIC50:  78.8nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ family of Ser/Thr kinases. The kinases t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Medivation Technologies

US Patent
LigandPNGBDBM280367(4-{[2-(5-chloro-2-fluorophenyl)-5-(pyrrolidin-1-yl...)
Affinity DataIC50:  78.8nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ family of Ser/Thr kinases. The kinases t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Medivation Technologies

US Patent
LigandPNGBDBM280367(4-{[2-(5-chloro-2-fluorophenyl)-5-(pyrrolidin-1-yl...)
Affinity DataIC50:  78.8nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetActivin receptor type-1B(Homo sapiens (Human))
Medivation Technologies

US Patent
LigandPNGBDBM280367(4-{[2-(5-chloro-2-fluorophenyl)-5-(pyrrolidin-1-yl...)
Affinity DataIC50:  89.6nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ3 family of Ser/Thr kinases. The kinases ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetActivin receptor type-1B(Homo sapiens (Human))
Medivation Technologies

US Patent
LigandPNGBDBM280367(4-{[2-(5-chloro-2-fluorophenyl)-5-(pyrrolidin-1-yl...)
Affinity DataIC50:  89.6nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ family of Ser/Thr kinases. The kinases t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetActivin receptor type-1B(Homo sapiens (Human))
Medivation Technologies

US Patent
LigandPNGBDBM280367(4-{[2-(5-chloro-2-fluorophenyl)-5-(pyrrolidin-1-yl...)
Affinity DataIC50:  89.6nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ family of Ser/Thr kinases. The kinases t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetActivin receptor type-1B(Homo sapiens (Human))
Medivation Technologies

US Patent
LigandPNGBDBM280367(4-{[2-(5-chloro-2-fluorophenyl)-5-(pyrrolidin-1-yl...)
Affinity DataIC50:  89.6nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
Medivation Technologies

US Patent
LigandPNGBDBM280367(4-{[2-(5-chloro-2-fluorophenyl)-5-(pyrrolidin-1-yl...)
Affinity DataIC50: >1.00E+4nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ family of Ser/Thr kinases. The kinases t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetActivin receptor type-1(Homo sapiens (Human))
Medivation Technologies

US Patent
LigandPNGBDBM280367(4-{[2-(5-chloro-2-fluorophenyl)-5-(pyrrolidin-1-yl...)
Affinity DataIC50: >1.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBone morphogenetic protein receptor type-1A(Homo sapiens (Human))
Medivation Technologies

US Patent
LigandPNGBDBM280367(4-{[2-(5-chloro-2-fluorophenyl)-5-(pyrrolidin-1-yl...)
Affinity DataIC50: >1.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBone morphogenetic protein 10(Homo sapiens (Human))
Medivation Technologies

US Patent
LigandPNGBDBM280367(4-{[2-(5-chloro-2-fluorophenyl)-5-(pyrrolidin-1-yl...)
Affinity DataIC50: >1.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
Medivation Technologies

US Patent
LigandPNGBDBM280367(4-{[2-(5-chloro-2-fluorophenyl)-5-(pyrrolidin-1-yl...)
Affinity DataIC50: >1.00E+4nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ3 family of Ser/Thr kinases. The kinases ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetActivin receptor type-1(Homo sapiens (Human))
Medivation Technologies

US Patent
LigandPNGBDBM280367(4-{[2-(5-chloro-2-fluorophenyl)-5-(pyrrolidin-1-yl...)
Affinity DataIC50: >1.00E+4nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ3 family of Ser/Thr kinases. The kinases ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBone morphogenetic protein receptor type-1A(Homo sapiens (Human))
Medivation Technologies

US Patent
LigandPNGBDBM280367(4-{[2-(5-chloro-2-fluorophenyl)-5-(pyrrolidin-1-yl...)
Affinity DataIC50: >1.00E+4nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ3 family of Ser/Thr kinases. The kinases ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBone morphogenetic protein receptor type-1B(Homo sapiens (Human))
Medivation Technologies

US Patent
LigandPNGBDBM280367(4-{[2-(5-chloro-2-fluorophenyl)-5-(pyrrolidin-1-yl...)
Affinity DataIC50: >1.00E+4nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ family of Ser/Thr kinases. The kinases t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBone morphogenetic protein receptor type-1A(Homo sapiens (Human))
Medivation Technologies

US Patent
LigandPNGBDBM280367(4-{[2-(5-chloro-2-fluorophenyl)-5-(pyrrolidin-1-yl...)
Affinity DataIC50: >1.00E+4nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ family of Ser/Thr kinases. The kinases t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetActivin receptor type-1(Homo sapiens (Human))
Medivation Technologies

US Patent
LigandPNGBDBM280367(4-{[2-(5-chloro-2-fluorophenyl)-5-(pyrrolidin-1-yl...)
Affinity DataIC50: >1.00E+4nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ family of Ser/Thr kinases. The kinases t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
Medivation Technologies

US Patent
LigandPNGBDBM280367(4-{[2-(5-chloro-2-fluorophenyl)-5-(pyrrolidin-1-yl...)
Affinity DataIC50: >1.00E+4nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ family of Ser/Thr kinases. The kinases t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBone morphogenetic protein receptor type-1B(Mus musculus (Mouse))
Medivation Technologies

US Patent
LigandPNGBDBM280367(4-{[2-(5-chloro-2-fluorophenyl)-5-(pyrrolidin-1-yl...)
Affinity DataIC50: >1.00E+4nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ family of Ser/Thr kinases. The kinases t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBone morphogenetic protein receptor type-1A(Homo sapiens (Human))
Medivation Technologies

US Patent
LigandPNGBDBM280367(4-{[2-(5-chloro-2-fluorophenyl)-5-(pyrrolidin-1-yl...)
Affinity DataIC50: >1.00E+4nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ family of Ser/Thr kinases. The kinases t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBone morphogenetic protein receptor type-1B(Homo sapiens (Human))
Medivation Technologies

US Patent
LigandPNGBDBM280367(4-{[2-(5-chloro-2-fluorophenyl)-5-(pyrrolidin-1-yl...)
Affinity DataIC50: >1.00E+4nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ3 family of Ser/Thr kinases. The kinases ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
Medivation Technologies

US Patent
LigandPNGBDBM280367(4-{[2-(5-chloro-2-fluorophenyl)-5-(pyrrolidin-1-yl...)
Affinity DataIC50: >1.00E+4nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ family of Ser/Thr kinases. The kinases t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetActivin receptor type-1(Homo sapiens (Human))
Medivation Technologies

US Patent
LigandPNGBDBM280367(4-{[2-(5-chloro-2-fluorophenyl)-5-(pyrrolidin-1-yl...)
Affinity DataIC50: >1.00E+4nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ family of Ser/Thr kinases. The kinases t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent