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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 14 hits in this display   

TargetHistone deacetylase 6(Homo sapiens (Human))
Ghent University

Curated by ChEMBL
LigandPNGBDBM50252388(CHEMBL4079541)
Affinity DataIC50:  25nMAssay Description:Inhibition of human HDAC6 after 15 mins by trypsin-coupled fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Ghent University

Curated by ChEMBL
LigandPNGBDBM50252388(CHEMBL4079541)
Affinity DataIC50:  31nMAssay Description:Inhibition of recombinant human full length N-terminal GST-tagged HDAC6 expressed in baculovirus infected Sf9 insect cells assessed as decrease in re...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Ghent University

Curated by ChEMBL
LigandPNGBDBM50252388(CHEMBL4079541)
Affinity DataIC50:  376nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Ghent University

Curated by ChEMBL
LigandPNGBDBM50252388(CHEMBL4079541)
Affinity DataIC50:  400nMAssay Description:Inhibition of human HDAC8 after 15 mins by trypsin-coupled fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
Ghent University

Curated by ChEMBL
LigandPNGBDBM50252388(CHEMBL4079541)
Affinity DataIC50:  700nMAssay Description:Inhibition of human HDAC10 after 15 mins by trypsin-coupled fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Ghent University

Curated by ChEMBL
LigandPNGBDBM50252388(CHEMBL4079541)
Affinity DataIC50:  800nMAssay Description:Inhibition of human HDAC1 after 15 mins by trypsin-coupled fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 7(Homo sapiens (Human))
Ghent University

Curated by ChEMBL
LigandPNGBDBM50252388(CHEMBL4079541)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of human HDAC7 after 15 mins by trypsin-coupled fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Ghent University

Curated by ChEMBL
LigandPNGBDBM50252388(CHEMBL4079541)
Affinity DataIC50:  1.13E+3nMAssay Description:Inhibition of recombinant human full length C-terminal His/FLAG-tagged HDAC1 expressed in baculovirus infected Sf9 insect cells assessed as decrease ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Ghent University

Curated by ChEMBL
LigandPNGBDBM50252388(CHEMBL4079541)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of human HDAC3 after 15 mins by by trypsin-coupled fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Ghent University

Curated by ChEMBL
LigandPNGBDBM50252388(CHEMBL4079541)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of human HDAC2 after 15 mins by trypsin-coupled fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Ghent University

Curated by ChEMBL
LigandPNGBDBM50252388(CHEMBL4079541)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of human HDAC4 after 15 mins by trypsin-coupled fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 11(Homo sapiens (Human))
Ghent University

Curated by ChEMBL
LigandPNGBDBM50252388(CHEMBL4079541)
Affinity DataIC50:  3.70E+3nMAssay Description:Inhibition of human HDAC11 after 15 mins by trypsin-coupled fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 9(Homo sapiens (Human))
Ghent University

Curated by ChEMBL
LigandPNGBDBM50252388(CHEMBL4079541)
Affinity DataIC50:  5.30E+3nMAssay Description:Inhibition of human HDAC9 after 15 mins by trypsin-coupled fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 5(Homo sapiens (Human))
Ghent University

Curated by ChEMBL
LigandPNGBDBM50252388(CHEMBL4079541)
Affinity DataIC50:  9.50E+3nMAssay Description:Inhibition of human HDAC5 after 15 mins by trypsin-coupled fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed