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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
10
hits in this display
Target
Cytochrome P450 3A4
(Homo sapiens (Human))
University Of Sharjah
Curated by
ChEMBL
Ligand
BDBM50568243
(CHEMBL4846752)
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Affinity Data
IC50: 233nM
Assay Description:
Inhibition of human CYP3A4 expressed in insect supersomes assessed as reduction in 10-hydroxymidazolam formation using midazolam as substrate measure...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
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Article
PubMed
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Target
Histone deacetylase 2
(Homo sapiens (Human))
University Of Sharjah
Curated by
ChEMBL
Ligand
BDBM50568243
(CHEMBL4846752)
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Affinity Data
IC50: 400nM
Assay Description:
Inhibition of C-terminal 6XHis-tagged human recombinant full length HDAC2 (1 to 488 residues) expressed in baculovirus-infected Sf9 cells assessed as...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
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Article
PubMed
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Target
Histone deacetylase 1
(Homo sapiens (Human))
University Of Sharjah
Curated by
ChEMBL
Ligand
BDBM50568243
(CHEMBL4846752)
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Affinity Data
IC50: 550nM
Assay Description:
Inhibition of C-terminal FLAG/His-tagged human recombinant HDAC1 (1 to 482 residues) expressed in baculovirus-infected Sf9 cells assessed as reductio...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
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Target
Cytochrome P450 2C9
(Homo sapiens (Human))
University Of Sharjah
Curated by
ChEMBL
Ligand
BDBM50568243
(CHEMBL4846752)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of human CYP2C9-1 expressed in insect supersomes assessed as reduction in HFC formation using MFC as substrate measured after 30 mins in p...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
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PC sid
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Article
PubMed
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Target
Histone deacetylase 9
(Homo sapiens (Human))
University Of Sharjah
Curated by
ChEMBL
Ligand
BDBM50568243
(CHEMBL4846752)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of C-terminal His-tagged human HDAC9 (604 to 1066 residues) expressed in baculovirus-infected Sf9 cells assessed as reduction in 7-amino-4...
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
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Article
PubMed
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Target
Histone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)
(Homo sapiens (Human))
University Of Sharjah
Curated by
ChEMBL
Ligand
BDBM50568243
(CHEMBL4846752)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of C-terminal His-tagged human recombinant full length HDAC3 (1 to 428 residues)/N-terminal GST-tagged human recombinant NCOR2 (395 to 489...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
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PC sid
In Depth
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Article
PubMed
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Target
Histone deacetylase 4
(Homo sapiens (Human))
University Of Sharjah
Curated by
ChEMBL
Ligand
BDBM50568243
(CHEMBL4846752)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of N-terminal GST-tagged/C-terminal His-tagged human recombinant HDAC4 (627 to 1084 residues) expressed in baculovirus-infected Sf9 cells ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
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Target
Histone deacetylase 5
(Homo sapiens (Human))
University Of Sharjah
Curated by
ChEMBL
Ligand
BDBM50568243
(CHEMBL4846752)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of N-terminal GST-tagged human recombinant full length HDAC5 expressed in baculovirus-infected Sf9 cells assessed as reduction in 7-amino-...
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
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Target
Histone deacetylase 7
(Homo sapiens (Human))
University Of Sharjah
Curated by
ChEMBL
Ligand
BDBM50568243
(CHEMBL4846752)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of N-terminal GST-tagged human HDAC7 (518 to end residues) expressed in baculovirus-infected Sf9 cells assessed as reduction in 7-amino-4-...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cytochrome P450 2D6
(Homo sapiens (Human))
University Of Sharjah
Curated by
ChEMBL
Ligand
BDBM50568243
(CHEMBL4846752)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of human CYP2D6 expressed in insect supersomes assessed as reduction in AHMC formation using AMMC as substrate measured after 40 mins in p...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI