Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 7 hits in this display   

TargetHistone deacetylase 6(Homo sapiens (Human))
University Of Toledo

Curated by ChEMBL

LigandBDBM50588565(CHEMBL5204550)Copy SMILESCopy InChI

Affinity DataIC50:  170nMAssay Description:Inhibition of full length C-terminal FLAG-tagged human recombinant HDAC6 expressed inSf9 insect cellsMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

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TargetHistone deacetylase 2(Homo sapiens (Human))
University Of Toledo

Curated by ChEMBL

LigandBDBM50588565(CHEMBL5204550)Copy SMILESCopy InChI

Affinity DataIC50:  330nMAssay Description:Inhibition of full length C-terminal his6-tagged human recombinant HDAC2 (1 to 488 residues)More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails PubMed
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TargetHistone deacetylase 8(Homo sapiens (Human))
University Of Toledo

Curated by ChEMBL

LigandBDBM50588565(CHEMBL5204550)Copy SMILESCopy InChI

Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of full length C-terminal his-tagged human recombinant HDAC8 expressed in Sf9 insect cellsMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails PubMed
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TargetHistone deacetylase(Homo sapiens (Human))
University Of Toledo

Curated by ChEMBL

LigandBDBM50588565(CHEMBL5204550)Copy SMILESCopy InChI

Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of HDAC in human HCT-116 cellsMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
B.MOADantibodypediaantibodypediaantibodypediaantibodypediaantibodypediaantibodypediaantibodypediaantibodypediaantibodypediaantibodypediaantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

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TargetHistone deacetylase 3(Homo sapiens (Human))
University Of Toledo

Curated by ChEMBL

LigandBDBM50588565(CHEMBL5204550)Copy SMILESCopy InChI

Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of full length C-terminal his6/FLAG-tagged human recombinant HDAC3 (1 to 2383 residues) expressed in Sf9 insect cellsMore data for this Ligand-Target Pair

Target InfoPDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails PubMed
Copy BDB DOI

TargetHistone deacetylase(Homo sapiens (Human))
University Of Toledo

Curated by ChEMBL

LigandBDBM50588565(CHEMBL5204550)Copy SMILESCopy InChI

Affinity DataIC50:  3.23E+3nMAssay Description:Inhibition of HDAC in human NCI-H522 cellsMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
B.MOADantibodypediaantibodypediaantibodypediaantibodypediaantibodypediaantibodypediaantibodypediaantibodypediaantibodypediaantibodypediaantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails PubMed
Copy BDB DOI

TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Toledo

Curated by ChEMBL

LigandBDBM50588565(CHEMBL5204550)Copy SMILESCopy InChI

Affinity DataIC50:  1.50E+5nMAssay Description:Inhibition of full length his6/FLAG-tagged human recombinant HDAC1(1 to 482 residues) expressed in Sf9 insect cellsMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails PubMed
Copy BDB DOI