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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 5 hits in this display   

TargetHistone deacetylase(Homo sapiens (Human))
European Institute Of Oncology

Curated by ChEMBL
LigandPNGBDBM50435606(CHEMBL2390996)
Affinity DataIC50:  113nMAssay Description:Inhibition of HDAC in human HeLa cells nuclear extract using Fluor de lys as substrate after 15 mins by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
European Institute Of Oncology

Curated by ChEMBL
LigandPNGBDBM50435606(CHEMBL2390996)
Affinity DataIC50:  130nMAssay Description:Inhibition of recombinant human HDAC3 after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
European Institute Of Oncology

Curated by ChEMBL
LigandPNGBDBM50435606(CHEMBL2390996)
Affinity DataIC50:  130nMAssay Description:Inhibition of HDAC3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
European Institute Of Oncology

Curated by ChEMBL
LigandPNGBDBM50435606(CHEMBL2390996)
Affinity DataIC50:  138nMAssay Description:Inhibition of recombinant human HDAC6 after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
European Institute Of Oncology

Curated by ChEMBL
LigandPNGBDBM50435606(CHEMBL2390996)
Affinity DataIC50:  199nMAssay Description:Inhibition of recombinant human HDAC2 after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed