Home
About
Info
Download
WebServices
Contact
Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
5
hits in this display
Target
Bone morphogenetic protein 1
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50216823
(2-(5-{(1R)-4-cyclohexyl-1-[2-(hydroxyamino)-2-oxoe...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 6nM
Assay Description:
Inhibition of human procollagen C-proteinase expressed in CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Zinc metalloproteinase dpy-31
(Brugia malayi)
University Of Glasgow
Curated by
ChEMBL
Ligand
BDBM50216823
(2-(5-{(1R)-4-cyclohexyl-1-[2-(hydroxyamino)-2-oxoe...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.00E+4nM
Assay Description:
Inhibition of recombinant Brugia malayi DPY-31 astacin domain expressed in Escherichia coli using Suc-Ala-Ala-Ala-pNA as substrate preincubated for 3...
More data for this Ligand-Target Pair
Target Info
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
72 kDa type IV collagenase
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50216823
(2-(5-{(1R)-4-cyclohexyl-1-[2-(hydroxyamino)-2-oxoe...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >3.00E+4nM
Assay Description:
Inhibition of MMP2
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Zinc metalloproteinase dpy-31
(Teladorsagia circumcincta)
University Of Glasgow
Curated by
ChEMBL
Ligand
BDBM50216823
(2-(5-{(1R)-4-cyclohexyl-1-[2-(hydroxyamino)-2-oxoe...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3.98E+4nM
Assay Description:
Inhibition of recombinant Teladorsagia circumcincta DPY-31 astacin domain expressed in Escherichia coli using Suc-Ala-Ala-Ala-pNA as substrate preinc...
More data for this Ligand-Target Pair
Target Info
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Interstitial collagenase
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50216823
(2-(5-{(1R)-4-cyclohexyl-1-[2-(hydroxyamino)-2-oxoe...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+5nM
Assay Description:
Inhibition of MMP1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI