Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 6 hits in this display   

TargetHistone deacetylase 6(Homo sapiens (Human))
University of Illinois At Chicago

LigandPNGBDBM24348(N-(4-{1-[2-(3-bromophenyl)-2-hydroxyethyl]-1H-1,2,...)
Affinity DataIC50:  4.40nMAssay Description:The inhibitory effects of compounds on histone deacetylase (HDAC) activity were determined using a fluorescence-based assay with electrophoretic sepa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
University of Illinois At Chicago

LigandPNGBDBM24348(N-(4-{1-[2-(3-bromophenyl)-2-hydroxyethyl]-1H-1,2,...)
Affinity DataIC50:  25.3nMAssay Description:The inhibitory effects of compounds on histone deacetylase (HDAC) activity were determined using a fluorescence-based assay with electrophoretic sepa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University of Illinois At Chicago

LigandPNGBDBM24348(N-(4-{1-[2-(3-bromophenyl)-2-hydroxyethyl]-1H-1,2,...)
Affinity DataIC50:  69.2nMpH: 7.5 T: 2°CAssay Description:The inhibitory effects of compounds on histone deacetylase (HDAC) activity were determined using a fluorescence-based assay with electrophoretic sepa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
University of Illinois At Chicago

LigandPNGBDBM24348(N-(4-{1-[2-(3-bromophenyl)-2-hydroxyethyl]-1H-1,2,...)
Affinity DataIC50:  86.5nMAssay Description:The inhibitory effects of compounds on histone deacetylase (HDAC) activity were determined using a fluorescence-based assay with electrophoretic sepa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
University of Illinois At Chicago

LigandPNGBDBM24348(N-(4-{1-[2-(3-bromophenyl)-2-hydroxyethyl]-1H-1,2,...)
Affinity DataIC50:  143nMpH: 7.5 T: 2°CAssay Description:The inhibitory effects of compounds on histone deacetylase (HDAC) activity were determined using a fluorescence-based assay with electrophoretic sepa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
University of Illinois At Chicago

LigandPNGBDBM24348(N-(4-{1-[2-(3-bromophenyl)-2-hydroxyethyl]-1H-1,2,...)
Affinity DataIC50:  3.13E+3nMAssay Description:The inhibitory effects of compounds on histone deacetylase (HDAC) activity were determined using a fluorescence-based assay with electrophoretic sepa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed