Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 6 hits in this display   

TargetHistone deacetylase 6(Homo sapiens (Human))
University of Illinois At Chicago

LigandPNGBDBM24356(N-(4-{1-[2-(3-bromophenyl)-2-hydroxyethyl]-1H-1,2,...)
Affinity DataIC50:  4.20nMAssay Description:The inhibitory effects of compounds on histone deacetylase (HDAC) activity were determined using a fluorescence-based assay with electrophoretic sepa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
University of Illinois At Chicago

LigandPNGBDBM24356(N-(4-{1-[2-(3-bromophenyl)-2-hydroxyethyl]-1H-1,2,...)
Affinity DataIC50:  15.1nMAssay Description:The inhibitory effects of compounds on histone deacetylase (HDAC) activity were determined using a fluorescence-based assay with electrophoretic sepa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University of Illinois At Chicago

LigandPNGBDBM24356(N-(4-{1-[2-(3-bromophenyl)-2-hydroxyethyl]-1H-1,2,...)
Affinity DataIC50:  69.9nMpH: 7.5 T: 2°CAssay Description:The inhibitory effects of compounds on histone deacetylase (HDAC) activity were determined using a fluorescence-based assay with electrophoretic sepa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
University of Illinois At Chicago

LigandPNGBDBM24356(N-(4-{1-[2-(3-bromophenyl)-2-hydroxyethyl]-1H-1,2,...)
Affinity DataIC50:  74.8nMAssay Description:The inhibitory effects of compounds on histone deacetylase (HDAC) activity were determined using a fluorescence-based assay with electrophoretic sepa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
University of Illinois At Chicago

LigandPNGBDBM24356(N-(4-{1-[2-(3-bromophenyl)-2-hydroxyethyl]-1H-1,2,...)
Affinity DataIC50:  216nMAssay Description:The inhibitory effects of compounds on histone deacetylase (HDAC) activity were determined using a fluorescence-based assay with electrophoretic sepa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
University of Illinois At Chicago

LigandPNGBDBM24356(N-(4-{1-[2-(3-bromophenyl)-2-hydroxyethyl]-1H-1,2,...)
Affinity DataIC50:  737nMAssay Description:The inhibitory effects of compounds on histone deacetylase (HDAC) activity were determined using a fluorescence-based assay with electrophoretic sepa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed