Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 6 hits in this display   

TargetHistone deacetylase 6(Homo sapiens (Human))
University of Illinois At Chicago

LigandPNGBDBM24350(N-(3-{1-[(4-fluorophenyl)methyl]-1H-1,2,3-triazol-...)
Affinity DataIC50:  2.60nMAssay Description:The inhibitory effects of compounds on histone deacetylase (HDAC) activity were determined using a fluorescence-based assay with electrophoretic sepa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
University of Illinois At Chicago

LigandPNGBDBM24350(N-(3-{1-[(4-fluorophenyl)methyl]-1H-1,2,3-triazol-...)
Affinity DataIC50:  4nMAssay Description:The inhibitory effects of compounds on histone deacetylase (HDAC) activity were determined using a fluorescence-based assay with electrophoretic sepa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University of Illinois At Chicago

LigandPNGBDBM24350(N-(3-{1-[(4-fluorophenyl)methyl]-1H-1,2,3-triazol-...)
Affinity DataIC50:  17.6nMpH: 7.5 T: 2°CAssay Description:The inhibitory effects of compounds on histone deacetylase (HDAC) activity were determined using a fluorescence-based assay with electrophoretic sepa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
University of Illinois At Chicago

LigandPNGBDBM24350(N-(3-{1-[(4-fluorophenyl)methyl]-1H-1,2,3-triazol-...)
Affinity DataIC50:  34.3nMAssay Description:The inhibitory effects of compounds on histone deacetylase (HDAC) activity were determined using a fluorescence-based assay with electrophoretic sepa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
University of Illinois At Chicago

LigandPNGBDBM24350(N-(3-{1-[(4-fluorophenyl)methyl]-1H-1,2,3-triazol-...)
Affinity DataIC50:  77.4nMpH: 7.5 T: 2°CAssay Description:The inhibitory effects of compounds on histone deacetylase (HDAC) activity were determined using a fluorescence-based assay with electrophoretic sepa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
University of Illinois At Chicago

LigandPNGBDBM24350(N-(3-{1-[(4-fluorophenyl)methyl]-1H-1,2,3-triazol-...)
Affinity DataIC50:  552nMAssay Description:The inhibitory effects of compounds on histone deacetylase (HDAC) activity were determined using a fluorescence-based assay with electrophoretic sepa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed