Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 12 hits in this display   

TargetHistone deacetylase 3(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM24351(N-hydroxy-N'-[3-(1-phenyl-1H-1,2,3-triazol-4-yl)ph...)
Affinity DataIC50:  7.20nMAssay Description:Inhibition of HDAC3 assessed as blockade of decorboxylation of carboxyfluorescein labeled acetylated peptide substrate after 17 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM24351(N-hydroxy-N'-[3-(1-phenyl-1H-1,2,3-triazol-4-yl)ph...)
Affinity DataIC50:  7.20nMAssay Description:The inhibitory effects of compounds on histone deacetylase (HDAC) activity were determined using a fluorescence-based assay with electrophoretic sepa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Illinois At Chicago

LigandPNGBDBM24351(N-hydroxy-N'-[3-(1-phenyl-1H-1,2,3-triazol-4-yl)ph...)
Affinity DataIC50:  9.60nMAssay Description:The inhibitory effects of compounds on histone deacetylase (HDAC) activity were determined using a fluorescence-based assay with electrophoretic sepa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Illinois At Chicago

LigandPNGBDBM24351(N-hydroxy-N'-[3-(1-phenyl-1H-1,2,3-triazol-4-yl)ph...)
Affinity DataIC50:  9.60nMAssay Description:Inhibition of HDAC6 assessed as blockade of decorboxylation of carboxyfluorescein labeled acetylated peptide substrate after 17 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University of Illinois At Chicago

LigandPNGBDBM24351(N-hydroxy-N'-[3-(1-phenyl-1H-1,2,3-triazol-4-yl)ph...)
Affinity DataIC50:  18nMpH: 7.5 T: 2°CAssay Description:The inhibitory effects of compounds on histone deacetylase (HDAC) activity were determined using a fluorescence-based assay with electrophoretic sepa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University of Illinois At Chicago

LigandPNGBDBM24351(N-hydroxy-N'-[3-(1-phenyl-1H-1,2,3-triazol-4-yl)ph...)
Affinity DataIC50:  18nMAssay Description:Inhibition of HDAC1 assessed as blockade of decorboxylation of carboxyfluorescein labeled acetylated peptide substrate after 17 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
University of Illinois At Chicago

LigandPNGBDBM24351(N-hydroxy-N'-[3-(1-phenyl-1H-1,2,3-triazol-4-yl)ph...)
Affinity DataIC50:  27.7nMAssay Description:The inhibitory effects of compounds on histone deacetylase (HDAC) activity were determined using a fluorescence-based assay with electrophoretic sepa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
University of Illinois At Chicago

LigandPNGBDBM24351(N-hydroxy-N'-[3-(1-phenyl-1H-1,2,3-triazol-4-yl)ph...)
Affinity DataIC50:  27.7nMAssay Description:Inhibition of HDAC10 assessed as blockade of decorboxylation of carboxyfluorescein labeled acetylated peptide substrate after 17 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM24351(N-hydroxy-N'-[3-(1-phenyl-1H-1,2,3-triazol-4-yl)ph...)
Affinity DataIC50:  63.9nMAssay Description:Inhibition of HDAC2 assessed as blockade of decorboxylation of carboxyfluorescein labeled acetylated peptide substrate after 17 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM24351(N-hydroxy-N'-[3-(1-phenyl-1H-1,2,3-triazol-4-yl)ph...)
Affinity DataIC50:  63.9nMpH: 7.5 T: 2°CAssay Description:The inhibitory effects of compounds on histone deacetylase (HDAC) activity were determined using a fluorescence-based assay with electrophoretic sepa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM24351(N-hydroxy-N'-[3-(1-phenyl-1H-1,2,3-triazol-4-yl)ph...)
Affinity DataIC50:  2.78E+3nMAssay Description:Inhibition of HDAC8 assessed as blockade of decorboxylation of carboxyfluorescein labeled acetylated peptide substrate after 17 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM24351(N-hydroxy-N'-[3-(1-phenyl-1H-1,2,3-triazol-4-yl)ph...)
Affinity DataIC50:  2.78E+3nMAssay Description:The inhibitory effects of compounds on histone deacetylase (HDAC) activity were determined using a fluorescence-based assay with electrophoretic sepa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed