Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 12 hits in this display
BDBM24351(N-hydroxy-N'-[3-(1-phenyl-1H-1,2,3-triazol-4-yl)ph...)
IC50: 7.20nMAssay Description:Inhibition of HDAC3 assessed as blockade of decorboxylation of carboxyfluorescein labeled acetylated peptide substrate after 17 hrsMore data for this Ligand-Target Pair
BDBM24351(N-hydroxy-N'-[3-(1-phenyl-1H-1,2,3-triazol-4-yl)ph...)
BDBM24351(N-hydroxy-N'-[3-(1-phenyl-1H-1,2,3-triazol-4-yl)ph...)
BDBM24351(N-hydroxy-N'-[3-(1-phenyl-1H-1,2,3-triazol-4-yl)ph...)
IC50: 9.60nMAssay Description:Inhibition of HDAC6 assessed as blockade of decorboxylation of carboxyfluorescein labeled acetylated peptide substrate after 17 hrsMore data for this Ligand-Target Pair
BDBM24351(N-hydroxy-N'-[3-(1-phenyl-1H-1,2,3-triazol-4-yl)ph...)
BDBM24351(N-hydroxy-N'-[3-(1-phenyl-1H-1,2,3-triazol-4-yl)ph...)
IC50: 18nMAssay Description:Inhibition of HDAC1 assessed as blockade of decorboxylation of carboxyfluorescein labeled acetylated peptide substrate after 17 hrsMore data for this Ligand-Target Pair
BDBM24351(N-hydroxy-N'-[3-(1-phenyl-1H-1,2,3-triazol-4-yl)ph...)
BDBM24351(N-hydroxy-N'-[3-(1-phenyl-1H-1,2,3-triazol-4-yl)ph...)
IC50: 27.7nMAssay Description:Inhibition of HDAC10 assessed as blockade of decorboxylation of carboxyfluorescein labeled acetylated peptide substrate after 17 hrsMore data for this Ligand-Target Pair
BDBM24351(N-hydroxy-N'-[3-(1-phenyl-1H-1,2,3-triazol-4-yl)ph...)
IC50: 63.9nMAssay Description:Inhibition of HDAC2 assessed as blockade of decorboxylation of carboxyfluorescein labeled acetylated peptide substrate after 17 hrsMore data for this Ligand-Target Pair
BDBM24351(N-hydroxy-N'-[3-(1-phenyl-1H-1,2,3-triazol-4-yl)ph...)
IC50: 63.9nMpH: 7.5 T: 2°CAssay Description:The inhibitory effects of compounds on histone deacetylase (HDAC) activity were determined using a fluorescence-based assay with electrophoretic sepa...More data for this Ligand-Target Pair
BDBM24351(N-hydroxy-N'-[3-(1-phenyl-1H-1,2,3-triazol-4-yl)ph...)
IC50: 2.78E+3nMAssay Description:Inhibition of HDAC8 assessed as blockade of decorboxylation of carboxyfluorescein labeled acetylated peptide substrate after 17 hrsMore data for this Ligand-Target Pair
BDBM24351(N-hydroxy-N'-[3-(1-phenyl-1H-1,2,3-triazol-4-yl)ph...)
IC50: 2.78E+3nMAssay Description:The inhibitory effects of compounds on histone deacetylase (HDAC) activity were determined using a fluorescence-based assay with electrophoretic sepa...More data for this Ligand-Target Pair