Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 6 hits in this display   

TargetHistone deacetylase 6(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50312627(CHEMBL1094707 | Octanedioic Acid-[3-(1-Cyclohexyl-...)
Affinity DataIC50:  3.30nMAssay Description:Inhibition of HDAC6 assessed as blockade of decorboxylation of carboxyfluorescein labeled acetylated peptide substrate after 17 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50312627(CHEMBL1094707 | Octanedioic Acid-[3-(1-Cyclohexyl-...)
Affinity DataIC50:  3.70nMAssay Description:Inhibition of HDAC3 assessed as blockade of decorboxylation of carboxyfluorescein labeled acetylated peptide substrate after 17 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50312627(CHEMBL1094707 | Octanedioic Acid-[3-(1-Cyclohexyl-...)
Affinity DataIC50:  8.60nMAssay Description:Inhibition of HDAC1 assessed as blockade of decorboxylation of carboxyfluorescein labeled acetylated peptide substrate after 17 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50312627(CHEMBL1094707 | Octanedioic Acid-[3-(1-Cyclohexyl-...)
Affinity DataIC50:  9.80nMAssay Description:Inhibition of HDAC10 assessed as blockade of decorboxylation of carboxyfluorescein labeled acetylated peptide substrate after 17 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50312627(CHEMBL1094707 | Octanedioic Acid-[3-(1-Cyclohexyl-...)
Affinity DataIC50:  27.5nMAssay Description:Inhibition of HDAC2 assessed as blockade of decorboxylation of carboxyfluorescein labeled acetylated peptide substrate after 17 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50312627(CHEMBL1094707 | Octanedioic Acid-[3-(1-Cyclohexyl-...)
Affinity DataIC50:  1.19E+3nMAssay Description:Inhibition of HDAC8 assessed as blockade of decorboxylation of carboxyfluorescein labeled acetylated peptide substrate after 17 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed