Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Homo sapiens (Human))
Indian Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50531370(CHEMBL4468076)
Affinity DataIC50:  748nMAssay Description:Inhibition of human recombinant full length C-terminal His-tagged HDAC3 (1 to 428 residues)/N-terminal GST-tagged NCOR2 (395 to 489 residues) express...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Indian Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50531370(CHEMBL4468076)
Affinity DataIC50:  1.03E+3nMAssay Description:Inhibition of recombinant human FLAG/His-tagged HDAC1 expressed in baculovirus expression system using Boc-l-Lys(Ac)-AMC as substrate preincubated up...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Indian Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50531370(CHEMBL4468076)
Affinity DataIC50:  1.82E+3nMAssay Description:Inhibition of recombinant human full-length HDAC2 expressed in baculovirus expression system using Boc-l-Lys(Ac)-AMC as substrate preincubated up to ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Indian Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50531370(CHEMBL4468076)
Affinity DataIC50:  2.99E+4nMAssay Description:Inhibition of HDAC8 (unknown origin) expressed in Escherichia coli using BML-KI-178 as substrate preincubated up to 3 hrs and measured after 35 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed