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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
7
hits in this display
Target
Histone deacetylase 1
(Homo sapiens (Human))
Imperial College
Curated by
ChEMBL
Ligand
BDBM50386451
(CHEMBL2047685)
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Affinity Data
IC50: 310nM
Assay Description:
Inhibition of human recombinant HDAC1 using Boc-lys(Ac)-AMC as substrate preincubated for 20 mins with substrate measured after 60 mins by fluorescen...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Histone deacetylase-like amidohydrolase
(Alcaligenes sp. (strain DSM 11172) (Bordetella sp....)
Imperial College
Curated by
ChEMBL
Ligand
BDBM50386451
(CHEMBL2047685)
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Affinity Data
IC50: 310nM
Assay Description:
Inhibition of Bordetella sp. (strain FB188) N-terminus His-tagged HDAH expressed in Escherichia coli BL21 (DE3)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Histone deacetylase 1
(Homo sapiens (Human))
Imperial College
Curated by
ChEMBL
Ligand
BDBM50386451
(CHEMBL2047685)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.01E+3nM
Assay Description:
Inhibition of recombinant full length C-terminal FLAG/His-tagged human HDAC1 expressed in baculovirus infected Sf9 cells using Boc-Lys(Ac)-AMC as sub...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histone deacetylase 6
(Homo sapiens (Human))
Imperial College
Curated by
ChEMBL
Ligand
BDBM50386451
(CHEMBL2047685)
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Copy InChI
Affinity Data
IC50: 1.70E+3nM
Assay Description:
Inhibition of human recombinant HDAC6 using Boc-lys(Ac)-AMC as substrate preincubated for 20 mins with substrate measured after 60 mins by fluorescen...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histone deacetylase 2
(Homo sapiens (Human))
Shenyang Pharmaceutical University
Curated by
ChEMBL
Ligand
BDBM50386451
(CHEMBL2047685)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of recombinant full length C-terminal FLAG-tagged human HDAC2 expressed in baculovirus infected Sf9 cells using Boc-Lys(Ac)-AMC as substra...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)
(Homo sapiens (Human))
Shenyang Pharmaceutical University
Curated by
ChEMBL
Ligand
BDBM50386451
(CHEMBL2047685)
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Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of C-terminal His-tagged recombinant human HDAC3 (1 to 428 residues)/N-terminal GST-tagged recombinant human NCoR2 (395 to 489 residues) c...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histone deacetylase 6
(Homo sapiens (Human))
Imperial College
Curated by
ChEMBL
Ligand
BDBM50386451
(CHEMBL2047685)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of recombinant full length C-terminal FLAG-tagged human HDAC6 expressed in baculovirus infected Sf9 cells using Boc-Lys(Ac)-AMC as substra...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI