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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 15 hits in this display   

TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D3(Homo sapiens (Human))
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50579532(CHEMBL4867598)
Affinity DataIC50:  27nMAssay Description:Inhibition of full length human CDK6 (1 to 326 end residues)/N-terminal GST-fusion tagged CyclinD3 (1 to 292 residues) expressed in baculovirus expre...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50579532(CHEMBL4867598)
Affinity DataIC50:  61nMAssay Description:Inhibition of full length human CDK2 (1 to 298 end residues)/N-terminal GST-tagged CyclinA2 (1 to 432 residues) expressed in baculovirus expression s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50579532(CHEMBL4867598)
Affinity DataIC50:  129nMAssay Description:Inhibition of recombiant human HDAC6 using fluorogenic HDAC substrate 3 measured after 30 mins by fluorescence microplate reader assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Homo sapiens (Human))
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50579532(CHEMBL4867598)
Affinity DataIC50:  276nMAssay Description:Inhibition of full length human CDK4 (1 to 303 residues)/N-terminal GST-fusion tagged CyclinD3 (1 to 292 residues) expressed in baculovirus expressio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 7(Homo sapiens (Human))
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50579532(CHEMBL4867598)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of HDAC7 (unknown origin) measured after 30 mins by fluorescence microplate reader assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50579532(CHEMBL4867598)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of HDAC8 (unknown origin) measured after 30 mins by fluorescence microplate reader assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 9(Homo sapiens (Human))
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50579532(CHEMBL4867598)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of recombinant human HDAC9 measured after 30 mins by fluorescence microplate reader assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 11(Homo sapiens (Human))
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50579532(CHEMBL4867598)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of recombinant human HDAC11 measured after 30 mins by fluorescence microplate reader assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 5(Homo sapiens (Human))
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50579532(CHEMBL4867598)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of HDAC5 (unknown origin) measured after 30 mins by fluorescence microplate reader assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50579532(CHEMBL4867598)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of HDAC4 (unknown origin) measured after 30 mins by fluorescence microplate reader assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Homo sapiens (Human))
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50579532(CHEMBL4867598)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of C-terminal His-tagged recombinant human HDAC3 (1 to 428 residues)/N-terminal GST-tagged recombinant human NCoR2 (395 to 489 residues) c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50579532(CHEMBL4867598)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of HDAC1 (unknown origin) measured after 30 mins by fluorescence microplate reader assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50579532(CHEMBL4867598)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of HDAC2 (unknown origin) measured after 30 mins by fluorescence microplate reader assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50579532(CHEMBL4867598)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant human SIRT2 measured after 30 mins by fluorescence microplate reader assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Homo sapiens (Human))
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50579532(CHEMBL4867598)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant human SIRT5 measured after 30 mins by fluorescence microplate reader assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed