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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 10 hits in this display   

TargetHistone deacetylase 6(Homo sapiens (Human))
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50587186(CHEMBL5088034)
Affinity DataIC50:  20nMAssay Description:Inhibition of HDAC6 (unknown origin) using Boc-Lys(acetyl)-AMC as fluorogenic substrate measured after 1 hr by flourescence plate reader methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Homo sapiens (Human))
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50587186(CHEMBL5088034)
Affinity DataIC50:  69nMAssay Description:Inhibition of C-terminal His-tagged recombinant human HDAC3 (1 to 428 residues)/N-terminal GST-tagged recombinant human NCoR2 (395 to 489 residues) c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50587186(CHEMBL5088034)
Affinity DataIC50:  72nMAssay Description:Inhibition of HDAC in human HeLa nuclear extract using Boc-Lys(acetyl)-AMC as fluorogenic substrate measured after 1 hr by flourescence plate reader ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50587186(CHEMBL5088034)
Affinity DataIC50:  150nMAssay Description:Inhibition of HDAC1 (unknown origin) using Boc-Lys(acetyl)-AMC as fluorogenic substrate measured after 1 hr by flourescence plate reader methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50587186(CHEMBL5088034)
Affinity DataIC50: >200nMAssay Description:Inhibition of full length human C-terminal His-tagged HDAC8 expressed in baculovirus infected Sf9 insect cells using Boc-Lys(acetyl)-AMC as fluorogen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 7(Homo sapiens (Human))
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50587186(CHEMBL5088034)
Affinity DataIC50: >200nMAssay Description:Inhibition of human N-terminal GST tagged HDAC7 (518 to end residues) expressed in baculovirus infected Sf9 insect cells using Boc-Lys(acetyl)-AMC as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 5(Homo sapiens (Human))
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50587186(CHEMBL5088034)
Affinity DataIC50: >200nMAssay Description:Inhibition of human HDAC5 using Boc-Lys(acetyl)-AMC as fluorogenic substrate measured after 1 hr by flourescence plate reader methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 9(Homo sapiens (Human))
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50587186(CHEMBL5088034)
Affinity DataIC50: >200nMAssay Description:Inhibition of human C-terminal His-tagged HDAC9 (604 to 1066 residues) expressed in baculovirus infected Sf9 insect cells using Boc-Lys(acetyl)-AMC a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50587186(CHEMBL5088034)
Affinity DataIC50: >200nMAssay Description:Inhibition of full length human HDAC2 using Boc-Lys(acetyl)-AMC as fluorogenic substrate measured after 1 hr by flourescence plate reader methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50587186(CHEMBL5088034)
Affinity DataIC50: >200nMAssay Description:Inhibition of human HDAC4 using Boc-Lys(acetyl)-AMC as fluorogenic substrate measured after 1 hr by flourescence plate reader methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed