Home
About
Info
Download
WebServices
Contact
Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
8
hits in this display
Target
Polyunsaturated fatty acid 5-lipoxygenase
(Rattus norvegicus)
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50015094
(CHEMBL152665 | N-Hydroxy-2-phenyl-acetamide | N-hy...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 158nM
Assay Description:
Logarithmic value of inhibitory concentration against 5-lipoxygenase in rat basophilic leukemia cells (RBL-1)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histone deacetylase 6
(Homo sapiens (Human))
Broad Institute Of Mit And Harvard
Curated by
ChEMBL
Ligand
BDBM50015094
(CHEMBL152665 | N-Hydroxy-2-phenyl-acetamide | N-hy...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.10E+3nM
T: 2°C
Assay Description:
Inhibition of HDAC6 (unknown origin) assessed as fluorescence intensity measured after 60 mins incubation at room temperature by trypsin-free microfl...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histone deacetylase 8
(Homo sapiens (Human))
Broad Institute Of Mit And Harvard
Curated by
ChEMBL
Ligand
BDBM50015094
(CHEMBL152665 | N-Hydroxy-2-phenyl-acetamide | N-hy...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.16E+4nM
T: 2°C
Assay Description:
Inhibition of HDAC8 (unknown origin) assessed as fluorescence intensity measured after 60 mins incubation at room temperature by trypsin-free microfl...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Elastase
(Pseudomonas aeruginosa)
The Scripps Research Institute
Curated by
ChEMBL
Ligand
BDBM50015094
(CHEMBL152665 | N-Hydroxy-2-phenyl-acetamide | N-hy...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.36E+4nM
Assay Description:
Antagonist activity at Pseudomonas aeruginosa LasB using Abz-Ala-Gly-Leu-Ala-p-Nitro-Benzyl-Amide as substrate incubated for 30 mins prior to substra...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histone deacetylase 4
(Homo sapiens (Human))
Broad Institute Of Mit And Harvard
Curated by
ChEMBL
Ligand
BDBM50015094
(CHEMBL152665 | N-Hydroxy-2-phenyl-acetamide | N-hy...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >3.33E+4nM
T: 2°C
Assay Description:
Inhibition of HDAC4 (unknown origin) assessed as fluorescence intensity measured after 60 mins incubation at room temperature by trypsin-free microfl...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histone deacetylase 2
(Homo sapiens (Human))
Broad Institute Of Mit And Harvard
Curated by
ChEMBL
Ligand
BDBM50015094
(CHEMBL152665 | N-Hydroxy-2-phenyl-acetamide | N-hy...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >3.33E+4nM
T: 2°C
Assay Description:
Inhibition of HDAC2 (unknown origin) assessed as fluorescence intensity measured after 60 mins incubation at room temperature by trypsin-free microfl...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Polyunsaturated fatty acid 5-lipoxygenase
(Rattus norvegicus)
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50015094
(CHEMBL152665 | N-Hydroxy-2-phenyl-acetamide | N-hy...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3.00E+5nM
Assay Description:
In vitro inhibitory activity against 5-lipoxygenase in rat basophilic leukemia cells(RBL-1)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Polyunsaturated fatty acid 5-lipoxygenase
(Rattus norvegicus)
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50015094
(CHEMBL152665 | N-Hydroxy-2-phenyl-acetamide | N-hy...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3.00E+5nM
Assay Description:
In vitro inhibitory activity against RBL-1 5-LO
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI