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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 6 hits in this display   

TargetHistone deacetylase 6(Homo sapiens (Human))
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50560884(CHEMBL4800426)
Affinity DataIC50:  30nMAssay Description:Inhibition of human recombinant HDAC6 using ZMAL (Z-Lys(Ac)-AMC) fluorogenic substrate incubated for 90 mins by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50560884(CHEMBL4800426)
Affinity DataIC50:  2.26E+3nMAssay Description:Inhibition of human recombinant HDAC2 using ZMAL (Z-Lys(Ac)-AMC) fluorogenic substrate incubated for 90 mins by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50560884(CHEMBL4800426)
Affinity DataIC50:  5.18E+3nMAssay Description:Inhibition of human recombinant HDAC1 using ZMAL (Z-Lys(Ac)-AMC) fluorogenic substrate incubated for 90 mins by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50560884(CHEMBL4800426)
Affinity DataIC50:  8.48E+3nMAssay Description:Inhibition of human recombinant HDAC3 using ZMAL (Z-Lys(Ac)-AMC) fluorogenic substrate incubated for 90 mins by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50560884(CHEMBL4800426)
Affinity DataIC50:  1.47E+4nMAssay Description:Inhibition of human recombinant HDAC8 using Boc-Lys-(epsilon-Tfa)-AMC fluorogenic substrate incubated for 90 mins by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50560884(CHEMBL4800426)
Affinity DataIC50:  5.54E+4nMAssay Description:Inhibition of human recombinant HDAC4 using Boc-Lys-(epsilon-Tfa)-AMC fluorogenic substrate incubated for 90 mins by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed