Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 8 hits in this display   

TargetHistone deacetylase 6(Homo sapiens (Human))
Ocean University Of China

Curated by ChEMBL
LigandPNGBDBM417063(4-((3,4-dihydroquinolin-1(2H)-yl)methyl)-N-hydroxy...)
Affinity DataIC50:  2.30nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Ocean University Of China

Curated by ChEMBL
LigandPNGBDBM417063(4-((3,4-dihydroquinolin-1(2H)-yl)methyl)-N-hydroxy...)
Affinity DataIC50:  14.6nMAssay Description:The effectiveness, or potency, of a present HDACI with respect to inhibiting the activity of an HDAC is measured by an IC50 value. The quantitative I...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM417063(4-((3,4-dihydroquinolin-1(2H)-yl)methyl)-N-hydroxy...)
Affinity DataIC50:  15nMAssay Description:Inhibition of full length recombinant C-terminal FLAG-His-tagged human HDAC1 expressed in baculovirus infected Sf21 insect cells using RHK-K(Ac)-AMC ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM417063(4-((3,4-dihydroquinolin-1(2H)-yl)methyl)-N-hydroxy...)
Affinity DataIC50:  5.23E+3nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Ocean University Of China

Curated by ChEMBL
LigandPNGBDBM417063(4-((3,4-dihydroquinolin-1(2H)-yl)methyl)-N-hydroxy...)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of full length recombinant N-terminal GST-tagged human HDAC6 expressed in baculovirus infected Sf9 insect cells using RHK-K(Ac)-AMC peptid...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM417063(4-((3,4-dihydroquinolin-1(2H)-yl)methyl)-N-hydroxy...)
Affinity DataIC50:  1.11E+4nMAssay Description:The effectiveness, or potency, of a present HDACI with respect to inhibiting the activity of an HDAC is measured by an IC50 value. The quantitative I...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 3(Homo sapiens (Human))
Ocean University Of China

Curated by ChEMBL
LigandPNGBDBM417063(4-((3,4-dihydroquinolin-1(2H)-yl)methyl)-N-hydroxy...)
Affinity DataIC50:  2.95E+4nMAssay Description:Inhibition of HDAC3 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Ocean University Of China

Curated by ChEMBL
LigandPNGBDBM417063(4-((3,4-dihydroquinolin-1(2H)-yl)methyl)-N-hydroxy...)
Affinity DataIC50:  3.28E+4nMAssay Description:Inhibition of HDAC2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed