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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
8
hits in this display
Target
Histone deacetylase
(Homo sapiens (Human))
Shandong University
Curated by
ChEMBL
Ligand
BDBM50547479
(CHEMBL4794290)
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Affinity Data
IC50: 63nM
Assay Description:
Inhibition of HDAC in human HeLa nuclear extract using Boc-Lys(acetyl)-AMC or Boc-Lys (triflouroacetyl)-AMC as substrate preincubated for 5 mins foll...
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histone deacetylase 1
(Homo sapiens (Human))
Shandong University
Curated by
ChEMBL
Ligand
BDBM50547479
(CHEMBL4794290)
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Copy InChI
Affinity Data
IC50: 66nM
Assay Description:
Inhibition of HDAC1 (unknown origin) in using Boc-Lys(acetyl)-AMC or Boc-Lys (triflouroacetyl)-AMC as substrate preincubated for 5 mins followed by s...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histone deacetylase 2
(Homo sapiens (Human))
Shandong University
Curated by
ChEMBL
Ligand
BDBM50547479
(CHEMBL4794290)
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Affinity Data
IC50: 198nM
Assay Description:
Inhibition of HDAC2 (unknown origin) in using Boc-Lys(acetyl)-AMC or Boc-Lys (triflouroacetyl)-AMC as substrate preincubated for 5 mins followed by s...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histone deacetylase 8
(Homo sapiens (Human))
Shandong University
Curated by
ChEMBL
Ligand
BDBM50547479
(CHEMBL4794290)
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Affinity Data
IC50: 1.09E+3nM
Assay Description:
Inhibition of HDAC8 (unknown origin) in using Boc-Lys(acetyl)-AMC or Boc-Lys (triflouroacetyl)-AMC as substrate preincubated for 5 mins followed by s...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Apoptosis regulator Bcl-2
(Homo sapiens (Human))
Shandong University
Curated by
ChEMBL
Ligand
BDBM50547479
(CHEMBL4794290)
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Affinity Data
EC50: >1.00E+4nM
Assay Description:
Binding affinity to full length His-tagged Bcl2 (unknown origin) preincubated for 30 min followed by 5-FAM Bid-BH3 addition and measured after 20 min...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Induced myeloid leukemia cell differentiation protein Mcl-1
(Homo sapiens (Human))
Shandong University
Curated by
ChEMBL
Ligand
BDBM50547479
(CHEMBL4794290)
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Copy InChI
Affinity Data
EC50: >1.00E+4nM
Assay Description:
Binding affinity to full length His-tagged Mcl1 (unknown origin) preincubated for 30 min followed by 5-FAM Bid-BH3 addition and measured after 20 min...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Apoptosis regulator BAX
(Homo sapiens (Human))
Shandong University
Curated by
ChEMBL
Ligand
BDBM50547479
(CHEMBL4794290)
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Affinity Data
EC50: 393nM
Assay Description:
Binding affinity to recombinant human full length His-tagged BAX expressed in Escherichia coli BL21 (DE3) cells preincubated for 30 min followed by F...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Bcl-2-like protein 1
(Homo sapiens (Human))
Shandong University
Curated by
ChEMBL
Ligand
BDBM50547479
(CHEMBL4794290)
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Copy InChI
Affinity Data
EC50: >1.00E+4nM
Assay Description:
Binding affinity to full length His-tagged Bcl-xl (unknown origin) preincubated for 30 min followed by 5-FAM Bid-BH3 addition and measured after 20 m...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI