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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
15
hits in this display
Target
Histone deacetylase 6
(Homo sapiens (Human))
University Of Illinois At Chicago
Curated by
ChEMBL
Ligand
BDBM50247556
(CHEMBL4104117)
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Affinity Data
IC50: 0.290nM
Assay Description:
Inhibition of HDAC6 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
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Target
Histone deacetylase 6
(Homo sapiens (Human))
University Of Illinois At Chicago
Curated by
ChEMBL
Ligand
BDBM50247556
(CHEMBL4104117)
Copy SMILES
Copy InChI
Affinity Data
IC50: 0.291nM
Assay Description:
Inhibition of full length recombinant human N-terminal GST-tagged HDAC6 expressed in baculovirus infected insect cells using RHK-K(Ac)-AMC as substra...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
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Article
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Target
Histone deacetylase 6
(Homo sapiens (Human))
University Of Illinois At Chicago
Curated by
ChEMBL
Ligand
BDBM50247556
(CHEMBL4104117)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.70nM
Assay Description:
Inhibition of HDAC6 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
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PubMed
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Target
Histone deacetylase 11
(Homo sapiens (Human))
Taipei Medical University
Curated by
ChEMBL
Ligand
BDBM50247556
(CHEMBL4104117)
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Affinity Data
IC50: 376nM
Assay Description:
Inhibition of recombinant human N-terminal Strep2-tagged HDAC11 (1 to 347 residues) expressed in baculovirus infected insect cells using Boc-Lys(TFA)...
More data for this Ligand-Target Pair
Target Info
NCI pathway
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KEGG
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Target
Histone deacetylase 7
(Homo sapiens (Human))
Taipei Medical University
Curated by
ChEMBL
Ligand
BDBM50247556
(CHEMBL4104117)
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Affinity Data
IC50: 709nM
Assay Description:
Inhibition of recombinant human N-terminal GST-tagged HDAC7 (518 to 991 residues) expressed in insect cells using Boc-K(TFA)-AMC as substrate after 6...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
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Target
Histone deacetylase 8
(Homo sapiens (Human))
Taipei Medical University
Curated by
ChEMBL
Ligand
BDBM50247556
(CHEMBL4104117)
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Affinity Data
IC50: 1.19E+3nM
Assay Description:
Inhibition of recombinant human C-terminal His-tagged/N-terminal Strep2-tagged HDAC8 (1 to 377 residues) expressed in insect cells using RHK-K(Ac)-AM...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
UniProtKB/SwissProt
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Target
Histone deacetylase 9
(Homo sapiens (Human))
Taipei Medical University
Curated by
ChEMBL
Ligand
BDBM50247556
(CHEMBL4104117)
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Affinity Data
IC50: 1.53E+3nM
Assay Description:
Inhibition of HDAC9 (unknown origin)
More data for this Ligand-Target Pair
Target Info
Reactome pathway
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Target
Histone deacetylase 5
(Homo sapiens (Human))
Taipei Medical University
Curated by
ChEMBL
Ligand
BDBM50247556
(CHEMBL4104117)
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Affinity Data
IC50: 3.11E+3nM
Assay Description:
Inhibition of recombinant human C-terminal His-tagged HDAC5 (656 to 1122 residues) expressed in insect cells using Boc-K(Ac)-AMC as substrate after 6...
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
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Target
Histone deacetylase 4
(Homo sapiens (Human))
Taipei Medical University
Curated by
ChEMBL
Ligand
BDBM50247556
(CHEMBL4104117)
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Affinity Data
IC50: 4.44E+3nM
Assay Description:
Inhibition of recombinant human C-terminal His-tagged/N-terminal GST-tagged HDAC4 (627 to 1084 residues) expressed in insect cells using Boc-K(Ac)-AM...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
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antibodypedia
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Target
Histone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)
(Homo sapiens (Human))
Taipei Medical University
Curated by
ChEMBL
Ligand
BDBM50247556
(CHEMBL4104117)
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Affinity Data
IC50: 7.75E+3nM
Assay Description:
Inhibition of full length recombinant human C-terminal His-tagged HDAC3/N-terminal GST-tagged NCOR2 (395 to 489 residues) expressed in insect cells u...
More data for this Ligand-Target Pair
Target Info
PDB
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antibodypedia
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Target
Histone deacetylase 1
(Homo sapiens (Human))
University Of Illinois At Chicago
Curated by
ChEMBL
Ligand
BDBM50247556
(CHEMBL4104117)
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Affinity Data
IC50: 9.55E+3nM
Assay Description:
Inhibition of HDAC1 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
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antibodypedia
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Target
Histone deacetylase 1
(Homo sapiens (Human))
University Of Illinois At Chicago
Curated by
ChEMBL
Ligand
BDBM50247556
(CHEMBL4104117)
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Affinity Data
IC50: 9.55E+3nM
Assay Description:
Inhibition of full length recombinant human C-terminal FLAG/His-tagged HDAC1 expressed in baculovirus infected sf21 cells using RHK-K(Ac)-AMC as subs...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
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In Depth
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Article
PubMed
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Target
Polyamine deacetylase HDAC10
(Homo sapiens (Human))
Taipei Medical University
Curated by
ChEMBL
Ligand
BDBM50247556
(CHEMBL4104117)
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Affinity Data
IC50: 9.79E+3nM
Assay Description:
Inhibition of human HDAC10 using RHKKAc as substrate
More data for this Ligand-Target Pair
Target Info
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
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antibodypedia
GoogleScholar
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In Depth
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Article
PubMed
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Target
Histone deacetylase 2
(Homo sapiens (Human))
Taipei Medical University
Curated by
ChEMBL
Ligand
BDBM50247556
(CHEMBL4104117)
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Affinity Data
IC50: 1.25E+4nM
Assay Description:
Inhibition of full length recombinant human C-terminal GST-tagged HDAC2 expressed in baculovirus infected insect cells using RHK-K(Ac)-AMC as substra...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
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Target
NAD-dependent protein deacetylase sirtuin-1
(Homo sapiens (Human))
Taipei Medical University
Curated by
ChEMBL
Ligand
BDBM50247556
(CHEMBL4104117)
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Affinity Data
IC50: >2.00E+4nM
Assay Description:
Inhibition of recombinant human N-terminal His-tagged SIRT1 (1 to 747 end residues) expressed in Escherichia coli using Ac-RHK-K(Ac)-AMC as substrate...
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
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PC cid
PC sid
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In Depth
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Article
PubMed
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