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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 11 hits in this display   

TargetHistone deacetylase 6(Homo sapiens (Human))
Reaction Biology

US Patent
LigandPNGBDBM402284((N-hydroxy-4-((3-oxoisothiazolo[5,4-b]pyridin-2(3H...)
Affinity DataIC50:  0.958nMAssay Description: I. Compound handling: Testing compounds were dissolved in 100% DMSO to a specific concentration. The serial dilution was conducted by epMotion 5070 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 8(Homo sapiens (Human))
Reaction Biology

US Patent
LigandPNGBDBM402284((N-hydroxy-4-((3-oxoisothiazolo[5,4-b]pyridin-2(3H...)
Affinity DataIC50:  27.1nMAssay Description: I. Compound handling: Testing compounds were dissolved in 100% DMSO to a specific concentration. The serial dilution was conducted by epMotion 5070 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 1(Homo sapiens (Human))
Reaction Biology

US Patent
LigandPNGBDBM402284((N-hydroxy-4-((3-oxoisothiazolo[5,4-b]pyridin-2(3H...)
Affinity DataIC50:  175nMAssay Description: I. Compound handling: Testing compounds were dissolved in 100% DMSO to a specific concentration. The serial dilution was conducted by epMotion 5070 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 5(Homo sapiens (Human))
Reaction Biology

US Patent
LigandPNGBDBM402284((N-hydroxy-4-((3-oxoisothiazolo[5,4-b]pyridin-2(3H...)
Affinity DataIC50:  508nMAssay Description: I. Compound handling: Testing compounds were dissolved in 100% DMSO to a specific concentration. The serial dilution was conducted by epMotion 5070 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 [395-489](Homo sapiens (Human))
Reaction Biology

US Patent
LigandPNGBDBM402284((N-hydroxy-4-((3-oxoisothiazolo[5,4-b]pyridin-2(3H...)
Affinity DataIC50:  1.31E+3nMAssay Description: I. Compound handling: Testing compounds were dissolved in 100% DMSO to a specific concentration. The serial dilution was conducted by epMotion 5070 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 9 [604-1066](Homo sapiens (Human))
Reaction Biology

US Patent
LigandPNGBDBM402284((N-hydroxy-4-((3-oxoisothiazolo[5,4-b]pyridin-2(3H...)
Affinity DataIC50:  1.41E+3nMAssay Description: I. Compound handling: Testing compounds were dissolved in 100% DMSO to a specific concentration. The serial dilution was conducted by epMotion 5070 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 7 [518-592](Homo sapiens (Human))
Reaction Biology

US Patent
LigandPNGBDBM402284((N-hydroxy-4-((3-oxoisothiazolo[5,4-b]pyridin-2(3H...)
Affinity DataIC50:  1.89E+3nMAssay Description: I. Compound handling: Testing compounds were dissolved in 100% DMSO to a specific concentration. The serial dilution was conducted by epMotion 5070 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 11(Homo sapiens (Human))
Reaction Biology

US Patent
LigandPNGBDBM402284((N-hydroxy-4-((3-oxoisothiazolo[5,4-b]pyridin-2(3H...)
Affinity DataIC50:  2.84E+3nMAssay Description: I. Compound handling: Testing compounds were dissolved in 100% DMSO to a specific concentration. The serial dilution was conducted by epMotion 5070 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 4 [627-1085](Homo sapiens (Human))
Reaction Biology

US Patent
LigandPNGBDBM402284((N-hydroxy-4-((3-oxoisothiazolo[5,4-b]pyridin-2(3H...)
Affinity DataIC50:  3.31E+3nMAssay Description: I. Compound handling: Testing compounds were dissolved in 100% DMSO to a specific concentration. The serial dilution was conducted by epMotion 5070 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
Reaction Biology

US Patent
LigandPNGBDBM402284((N-hydroxy-4-((3-oxoisothiazolo[5,4-b]pyridin-2(3H...)
Affinity DataIC50:  4.26E+3nMAssay Description: I. Compound handling: Testing compounds were dissolved in 100% DMSO to a specific concentration. The serial dilution was conducted by epMotion 5070 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 2(Homo sapiens (Human))
Reaction Biology

US Patent
LigandPNGBDBM402284((N-hydroxy-4-((3-oxoisothiazolo[5,4-b]pyridin-2(3H...)
Affinity DataIC50:  5.40E+3nMAssay Description: I. Compound handling: Testing compounds were dissolved in 100% DMSO to a specific concentration. The serial dilution was conducted by epMotion 5070 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent