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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 12 hits in this display   

TargetHistone deacetylase 8(Homo sapiens (Human))
Roche Pharmaceutical Research And Early Development

Curated by ChEMBL
LigandPNGBDBM50027664(CHEMBL3338404)
Affinity DataIC50:  30nMAssay Description:Inhibition of HDAC8 (unknown origin) using fluorogenic peptide as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Roche Pharmaceutical Research And Early Development

Curated by ChEMBL
LigandPNGBDBM50027664(CHEMBL3338404)
Affinity DataIC50:  50nMAssay Description:Inhibition of HDAC6 (unknown origin) using fluorogenic peptide as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Roche Pharmaceutical Research And Early Development

Curated by ChEMBL
LigandPNGBDBM50027664(CHEMBL3338404)
Affinity DataIC50:  6.59E+3nMAssay Description:Inhibition of HDAC3 (unknown origin) using fluorogenic peptide as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Roche Pharmaceutical Research And Early Development

Curated by ChEMBL
LigandPNGBDBM50027664(CHEMBL3338404)
Affinity DataIC50:  2.13E+4nMAssay Description:Inhibition of HDAC1 (unknown origin) using fluorogenic peptide as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 5(Homo sapiens (Human))
Roche Pharmaceutical Research And Early Development

Curated by ChEMBL
LigandPNGBDBM50027664(CHEMBL3338404)
Affinity DataIC50:  3.60E+4nMAssay Description:Inhibition of HDAC5 (unknown origin) using fluorogenic peptide as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 7(Homo sapiens (Human))
Roche Pharmaceutical Research And Early Development

Curated by ChEMBL
LigandPNGBDBM50027664(CHEMBL3338404)
Affinity DataIC50:  6.07E+4nMAssay Description:Inhibition of HDAC7 (unknown origin) using fluorogenic peptide as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 9(Homo sapiens (Human))
Roche Pharmaceutical Research And Early Development

Curated by ChEMBL
LigandPNGBDBM50027664(CHEMBL3338404)
Affinity DataIC50:  6.58E+4nMAssay Description:Inhibition of HDAC9 (unknown origin) using fluorogenic peptide as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Roche Pharmaceutical Research And Early Development

Curated by ChEMBL
LigandPNGBDBM50027664(CHEMBL3338404)
Affinity DataIC50:  6.78E+4nMAssay Description:Inhibition of HDAC4 (unknown origin) using fluorogenic peptide as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
Roche Pharmaceutical Research And Early Development

Curated by ChEMBL
LigandPNGBDBM50027664(CHEMBL3338404)
Affinity DataIC50:  7.11E+4nMAssay Description:Inhibition of HDAC10 (unknown origin) using fluorogenic peptide as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 11(Homo sapiens (Human))
Roche Pharmaceutical Research And Early Development

Curated by ChEMBL
LigandPNGBDBM50027664(CHEMBL3338404)
Affinity DataIC50:  7.53E+4nMAssay Description:Inhibition of HDAC11 (unknown origin) using fluorogenic peptide as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Roche Pharmaceutical Research And Early Development

Curated by ChEMBL
LigandPNGBDBM50027664(CHEMBL3338404)
Affinity DataIC50:  1.09E+5nMAssay Description:Inhibition of HDAC2 (unknown origin) using fluorogenic peptide as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Roche Pharmaceutical Research And Early Development

Curated by ChEMBL
LigandPNGBDBM50027664(CHEMBL3338404)
Affinity DataEC50:  3.45E+3nMAssay Description:Inhibition of HDAC6 in human A549 cells assessed as tubulin acetylation after 17 to 18 hrs by cytoblot assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed