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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
3
hits in this display
Target
Histone deacetylase 8
(Homo sapiens (Human))
Howard Hughes Medical Institute
Curated by
ChEMBL
Ligand
BDBM50342751
(CHEMBL1771485 | N-hydroxy-3-(2-(4-(prop-2-ynyloxy)...)
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Affinity Data
IC50: 29nM
Assay Description:
Inhibition of full length HDAC8 assessed as 7-amino-4-methylcoumarin release from fluorophore conjugated substrate after 5 mins by fluorescence assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
In Depth
Details
Article
PubMed
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Target
Histone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)
(Homo sapiens (Human))
Howard Hughes Medical Institute
Curated by
ChEMBL
Ligand
BDBM50342751
(CHEMBL1771485 | N-hydroxy-3-(2-(4-(prop-2-ynyloxy)...)
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Affinity Data
IC50: 6.20E+3nM
Assay Description:
Inhibition of full length HDAC3/NCoR2 assessed as 7-amino-4-methylcoumarin release from fluorophore conjugated substrate after 5 mins by fluorescence...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histone deacetylase 2
(Homo sapiens (Human))
Howard Hughes Medical Institute
Curated by
ChEMBL
Ligand
BDBM50342751
(CHEMBL1771485 | N-hydroxy-3-(2-(4-(prop-2-ynyloxy)...)
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Copy InChI
Affinity Data
IC50: 6.30E+3nM
Assay Description:
Inhibition of full length HDAC2 assessed as 7-amino-4-methylcoumarin release from fluorophore conjugated substrate after 5 mins by fluorescence assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI