Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetHistone deacetylase 8(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50458433(CHEMBL4210091)
Affinity DataIC50:  910nMAssay Description:Inhibition of HDAC8 (unknown origin) using Boc-Lys(trifluoroacetyl)-AMC as substrate preincubated for 5 mins followed by substrate addition measured ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50458433(CHEMBL4210091)
Affinity DataIC50:  6.70E+3nMAssay Description:Inhibition of HDAC6 (unknown origin) using Boc-Lys(acetyl)-AMC as substrate preincubated for 5 mins followed by substrate addition measured after 30 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase (HDAC1 and HDAC2)(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50458433(CHEMBL4210091)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of HDAC1/2 in human HeLa nuclear extract using Boc-Lys(acetyl)-AMC as substrate preincubated for 5 mins followed by substrate addition mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50458433(CHEMBL4210091)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of HDAC2 (unknown origin) using Boc-Lys(acetyl)-AMC as substrate preincubated for 5 mins followed by substrate addition measured after 30 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed