Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 8 hits in this display   

TargetHistone deacetylase 1(Human)
Chroma Therapeutics

Curated by ChEMBL

LigandBDBM50347385(CHEMBL1801250)Copy SMILESCopy InChI

Affinity DataIC50:  3nMAssay Description:Inhibition of human recombinant HDAC1 using fluor de Lys as substrate by fluorometric analysisMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sid

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TargetHistone deacetylase 2(Human)
Chroma Therapeutics

Curated by ChEMBL

LigandBDBM50347385(CHEMBL1801250)Copy SMILESCopy InChI

Affinity DataIC50:  4nMAssay Description:Inhibition of human recombinant HDAC2 using fluor de Lys as substrate by fluorometric analysisMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sid

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TargetHistone deacetylase 3(Human)
Chroma Therapeutics

Curated by ChEMBL

LigandBDBM50347385(CHEMBL1801250)Copy SMILESCopy InChI

Affinity DataIC50:  7nMAssay Description:Inhibition of human recombinant HDAC3 using fluor de Lys as substrate by fluorometric analysisMore data for this Ligand-Target Pair

Target InfoPDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sid

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TargetHistone deacetylase 5(Human)
Chroma Therapeutics

Curated by ChEMBL

LigandBDBM50347385(CHEMBL1801250)Copy SMILESCopy InChI

Affinity DataIC50:  200nMAssay Description:Inhibition of human recombinant HDAC5 using fluor de Lys as substrate by fluorometric analysisMore data for this Ligand-Target Pair

Target InfoReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sid

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TargetHistone deacetylase 6(Human)
Chroma Therapeutics

Curated by ChEMBL

LigandBDBM50347385(CHEMBL1801250)Copy SMILESCopy InChI

Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of human recombinant HDAC6 using fluor de Lys as substrate by fluorometric analysisMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sid

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TargetCytochrome P450 3A4(Human)
Chroma Therapeutics

Curated by ChEMBL

LigandBDBM50347385(CHEMBL1801250)Copy SMILESCopy InChI

Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sid

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TargetCytochrome P450 2D6(Human)
Chroma Therapeutics

Curated by ChEMBL

LigandBDBM50347385(CHEMBL1801250)Copy SMILESCopy InChI

Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sid

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TargetCytochrome P450 2C19(Human)
Chroma Therapeutics

Curated by ChEMBL

LigandBDBM50347385(CHEMBL1801250)Copy SMILESCopy InChI

Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI