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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
8
hits in this display
Target
Carbonic anhydrase 2
(Homo sapiens (Human))
Universita Degli Studi
Ligand
BDBM11379
(Hydroxysulfonamide 60 | N-hydroxy-3-nitrobenzene-1...)
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Affinity Data
Ki: 5nM
Assay Description:
Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
KEGG
PC cid
PC sid
Patents
In Depth
Details
Article
PubMed
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Target
Carbonic anhydrase 4
(Bos taurus (bovine))
Universita Degli Studi
Ligand
BDBM11379
(Hydroxysulfonamide 60 | N-hydroxy-3-nitrobenzene-1...)
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Affinity Data
Ki: 24nM
Assay Description:
Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
KEGG
PC cid
PC sid
Patents
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Matrix metalloproteinase-9
(Homo sapiens (Human))
Universita Degli Studi
Ligand
BDBM11379
(Hydroxysulfonamide 60 | N-hydroxy-3-nitrobenzene-1...)
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Affinity Data
Ki: 1.30E+4nM
Assay Description:
Initial rates for the hydrolysis of the thioester substrate AcProLeuGly-S-LeuLeuGlyOEt, coupled to the reaction with 5,5-dithiobis(2-nitrobenzoic aci...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
KEGG
PC cid
PC sid
Patents
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Neutrophil collagenase
(Homo sapiens (Human))
Universita Degli Studi
Ligand
BDBM11379
(Hydroxysulfonamide 60 | N-hydroxy-3-nitrobenzene-1...)
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Affinity Data
Ki: 1.60E+4nM
Assay Description:
Initial rates for the hydrolysis of the thioester substrate AcProLeuGly-S-LeuLeuGlyOEt, coupled to the reaction with 5,5-dithiobis(2-nitrobenzoic aci...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
KEGG
PC cid
PC sid
Patents
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 1
(Homo sapiens (Human))
Universita Degli Studi
Ligand
BDBM11379
(Hydroxysulfonamide 60 | N-hydroxy-3-nitrobenzene-1...)
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Affinity Data
Ki: 1.70E+4nM
Assay Description:
Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
KEGG
PC cid
PC sid
Patents
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
72 kDa type IV collagenase
(Homo sapiens (Human))
Universita Degli Studi
Ligand
BDBM11379
(Hydroxysulfonamide 60 | N-hydroxy-3-nitrobenzene-1...)
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Affinity Data
Ki: 2.30E+4nM
Assay Description:
Initial rates for the hydrolysis of the thioester substrate AcProLeuGly-S-LeuLeuGlyOEt, coupled to the reaction with 5,5-dithiobis(2-nitrobenzoic aci...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
KEGG
PC cid
PC sid
Patents
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Collagenase ColG
(Clostridium histolyticum)
Universita Degli Studi
Ligand
BDBM11379
(Hydroxysulfonamide 60 | N-hydroxy-3-nitrobenzene-1...)
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Affinity Data
Ki: 3.20E+4nM
Assay Description:
The rate of hydrolysis was determined from the change in absorbance at 324 nm using an extinction coefficient, 24700 M-1 cm-1 for FALGPA. Initial vel...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
KEGG
PC cid
PC sid
Patents
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Interstitial collagenase
(Homo sapiens (Human))
Universita Degli Studi
Ligand
BDBM11379
(Hydroxysulfonamide 60 | N-hydroxy-3-nitrobenzene-1...)
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Copy InChI
Affinity Data
Ki: 3.70E+4nM
Assay Description:
Initial rates for the hydrolysis of the thioester substrate AcProLeuGly-S-LeuLeuGlyOEt, coupled to the reaction with 5,5-dithiobis(2-nitrobenzoic aci...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
KEGG
PC cid
PC sid
Patents
In Depth
Details
Article
PubMed
Copy BDB DOI