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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
9
hits in this display
Target
Carbonic anhydrase 2
(Homo sapiens (Human))
Universita Degli Studi
Ligand
BDBM11372
(CHEMBL55310 | Hydroxysulfonamide 53 | N-hydroxyben...)
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Affinity Data
Ki: 26nM
Assay Description:
Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
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CHEMBL
MMDB
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Article
PubMed
PDB
3D Structure (crystal)
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Target
Carbonic anhydrase 4
(Bos taurus (bovine))
Universita Degli Studi
Ligand
BDBM11372
(CHEMBL55310 | Hydroxysulfonamide 53 | N-hydroxyben...)
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Affinity Data
Ki: 74nM
Assay Description:
Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
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CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
In Depth
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Article
PubMed
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Target
Carbonic anhydrase 1
(Homo sapiens (Human))
Universita Degli Studi
Ligand
BDBM11372
(CHEMBL55310 | Hydroxysulfonamide 53 | N-hydroxyben...)
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Affinity Data
Ki: 1.80E+4nM
Assay Description:
Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
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CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
In Depth
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Article
PubMed
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Target
72 kDa type IV collagenase
(Homo sapiens (Human))
Universita Degli Studi
Ligand
BDBM11372
(CHEMBL55310 | Hydroxysulfonamide 53 | N-hydroxyben...)
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Affinity Data
Ki: 7.00E+4nM
Assay Description:
Initial rates for the hydrolysis of the thioester substrate AcProLeuGly-S-LeuLeuGlyOEt, coupled to the reaction with 5,5-dithiobis(2-nitrobenzoic aci...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
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CHEMBL
MMDB
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PC sid
PDB
Patents
In Depth
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Article
PubMed
Copy BDB DOI
Target
Neutrophil collagenase
(Homo sapiens (Human))
Universita Degli Studi
Ligand
BDBM11372
(CHEMBL55310 | Hydroxysulfonamide 53 | N-hydroxyben...)
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Affinity Data
Ki: 7.40E+4nM
Assay Description:
Initial rates for the hydrolysis of the thioester substrate AcProLeuGly-S-LeuLeuGlyOEt, coupled to the reaction with 5,5-dithiobis(2-nitrobenzoic aci...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Matrix metalloproteinase-9
(Homo sapiens (Human))
Universita Degli Studi
Ligand
BDBM11372
(CHEMBL55310 | Hydroxysulfonamide 53 | N-hydroxyben...)
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Affinity Data
Ki: 7.80E+4nM
Assay Description:
Initial rates for the hydrolysis of the thioester substrate AcProLeuGly-S-LeuLeuGlyOEt, coupled to the reaction with 5,5-dithiobis(2-nitrobenzoic aci...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Interstitial collagenase
(Homo sapiens (Human))
Universita Degli Studi
Ligand
BDBM11372
(CHEMBL55310 | Hydroxysulfonamide 53 | N-hydroxyben...)
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Affinity Data
Ki: 7.90E+4nM
Assay Description:
Initial rates for the hydrolysis of the thioester substrate AcProLeuGly-S-LeuLeuGlyOEt, coupled to the reaction with 5,5-dithiobis(2-nitrobenzoic aci...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Collagenase ColG
(Clostridium histolyticum)
Universita Degli Studi
Ligand
BDBM11372
(CHEMBL55310 | Hydroxysulfonamide 53 | N-hydroxyben...)
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Affinity Data
Ki: 8.30E+4nM
Assay Description:
The rate of hydrolysis was determined from the change in absorbance at 324 nm using an extinction coefficient, 24700 M-1 cm-1 for FALGPA. Initial vel...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
In Depth
Details
Article
PubMed
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Target
Aldehyde dehydrogenase 1A1
(Rattus norvegicus)
University Of Minnesota
Curated by
ChEMBL
Ligand
BDBM11372
(CHEMBL55310 | Hydroxysulfonamide 53 | N-hydroxyben...)
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Affinity Data
IC50: 4.80E+4nM
Assay Description:
In vitro inhibition against yeast Alcohol dehydrogenase
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
In Depth
Details
Article
PubMed
Copy BDB DOI