Home
About
Info
Download
WebServices
Contact
Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
12
hits in this display
Target
Type IV secretion-like conjugative transfer relaxase protein TraI
(Escherichia coli (strain SMS-3-5 / SECEC))
University Of North Carolina
Curated by
ChEMBL
Ligand
BDBM50162816
(CHEMBL180570 | Medronic acid | Methylene diphsphon...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 3nM
Assay Description:
Inhibition of Escherichia coli F plasmid TraI relaxase Y16F mutant assessed as oriT ssDNA cleavage by competitive inhibition assay
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Fe(3+)-Zn(2+) purple acid phosphatase
(Phaseolus vulgaris)
The University Of Queensland
Curated by
ChEMBL
Ligand
BDBM50162816
(CHEMBL180570 | Medronic acid | Methylene diphsphon...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.40E+5nM
Assay Description:
Inhibition of red kidney beans purple acid phosphatase
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 5A, mitochondrial
(Homo sapiens (Human))
University Of Montpellier
Curated by
ChEMBL
Ligand
BDBM50162816
(CHEMBL180570 | Medronic acid | Methylene diphsphon...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 7.30E+5nM
Assay Description:
Binding affinity towards recombinant human mitochondrial carbonic anhydrase V
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 9
(Homo sapiens (Human))
University Of Montpellier
Curated by
ChEMBL
Ligand
BDBM50162816
(CHEMBL180570 | Medronic acid | Methylene diphsphon...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 8.60E+5nM
Assay Description:
Binding affinity owards recombinant human transmembrane carbonic anhydrase IX
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 2
(Homo sapiens (Human))
University Of Montpellier
Curated by
ChEMBL
Ligand
BDBM50162816
(CHEMBL180570 | Medronic acid | Methylene diphsphon...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.25E+6nM
Assay Description:
Binding affinity towards human cytosolic carbonic anhydrase II
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 4
(Homo sapiens (Human))
University Of Montpellier
Curated by
ChEMBL
Ligand
BDBM50162816
(CHEMBL180570 | Medronic acid | Methylene diphsphon...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 5.34E+6nM
Assay Description:
Binding affinity towards human membrane associated carbonic anhydrase IV
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Ornithine transcarbamylase, mitochondrial
(Homo sapiens (Human))
Universit£Tstrasse 16
Curated by
ChEMBL
Ligand
BDBM50162816
(CHEMBL180570 | Medronic acid | Methylene diphsphon...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 9.00E+6nM
pH: 8.0
Assay Description:
Binding affinity against ornithine transcarbamoylase (OTC) produced by Streptococcus faecalis The buffer taken for this study is 50 mM Tris.HCl, 0.5 ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Ornithine transcarbamylase, mitochondrial
(Homo sapiens (Human))
Universit£Tstrasse 16
Curated by
ChEMBL
Ligand
BDBM50162816
(CHEMBL180570 | Medronic acid | Methylene diphsphon...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >2.00E+7nM
pH: 7.0
Assay Description:
Binding affinity against ornithine transcarbamoylase (OTC) produced by Streptococcus faecalis The buffer taken for this study is 50 mM Tris.HCl, 0.5 ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Ornithine transcarbamylase, mitochondrial
(Homo sapiens (Human))
Universit£Tstrasse 16
Curated by
ChEMBL
Ligand
BDBM50162816
(CHEMBL180570 | Medronic acid | Methylene diphsphon...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >2.00E+7nM
pH: 6.0
Assay Description:
Binding affinity against ornithine transcarbamoylase (OTC) produced by Streptococcus faecalis The buffer taken for this study is 50 mM maleate, 0.5 m...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
72 kDa type IV collagenase
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM50162816
(CHEMBL180570 | Medronic acid | Methylene diphsphon...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 4.90E+4nM
Assay Description:
Inhibition of human recombinant MMP-2 pretreated for 30 mins measured 2 to 4 hrs after Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrate addition by fluo...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 9
(Homo sapiens (Human))
University Of Montpellier
Curated by
ChEMBL
Ligand
BDBM50162816
(CHEMBL180570 | Medronic acid | Methylene diphsphon...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 8.60E+5nM
Assay Description:
Inhibition of human recombinant carbonic anhydrase 9 pretreated for 15 mins by stopped flow CO2 hydrase assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 2
(Homo sapiens (Human))
University Of Montpellier
Curated by
ChEMBL
Ligand
BDBM50162816
(CHEMBL180570 | Medronic acid | Methylene diphsphon...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.25E+6nM
Assay Description:
Inhibition of human recombinant carbonic anhydrase 2 pretreated for 15 mins by stopped flow CO2 hydrase assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI