Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 22 hits in this display   

TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50213737(7-nitro-1,1-dioxo-3-(2-phenoxy-phenylamino)-1,4-di...)
Affinity DataIC50:  54nMAssay Description:Displacement of human recombinant [125I]IL8 from CXCR2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50213737(7-nitro-1,1-dioxo-3-(2-phenoxy-phenylamino)-1,4-di...)
Affinity DataIC50:  490nMAssay Description:Antagonist activity at CXCR2 receptor expressed in CHOK1 cells assessed as human IL8-induced calcium mobilization by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50213737(7-nitro-1,1-dioxo-3-(2-phenoxy-phenylamino)-1,4-di...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of adrenergic alpha-1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50213737(7-nitro-1,1-dioxo-3-(2-phenoxy-phenylamino)-1,4-di...)
Affinity DataIC50: >3.20E+3nMAssay Description:Inhibition of histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50213737(7-nitro-1,1-dioxo-3-(2-phenoxy-phenylamino)-1,4-di...)
Affinity DataIC50: >3.20E+3nMAssay Description:Inhibition of dopamine D2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50213737(7-nitro-1,1-dioxo-3-(2-phenoxy-phenylamino)-1,4-di...)
Affinity DataIC50: >3.20E+3nMAssay Description:Inhibition of 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50213737(7-nitro-1,1-dioxo-3-(2-phenoxy-phenylamino)-1,4-di...)
Affinity DataIC50: >3.20E+3nMAssay Description:Inhibition of 5HT1D receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50213737(7-nitro-1,1-dioxo-3-(2-phenoxy-phenylamino)-1,4-di...)
Affinity DataIC50: >3.20E+3nMAssay Description:Inhibition of 5HT1B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50213737(7-nitro-1,1-dioxo-3-(2-phenoxy-phenylamino)-1,4-di...)
Affinity DataIC50: >3.20E+3nMAssay Description:Inhibition of dopamine D3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50213737(7-nitro-1,1-dioxo-3-(2-phenoxy-phenylamino)-1,4-di...)
Affinity DataIC50:  7.60E+3nMAssay Description:Displacement of human recombinant [125I]IL8 from CXCR1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50213737(7-nitro-1,1-dioxo-3-(2-phenoxy-phenylamino)-1,4-di...)
Affinity DataIC50: >7.90E+3nMAssay Description:Inhibition of 5HT6 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50213737(7-nitro-1,1-dioxo-3-(2-phenoxy-phenylamino)-1,4-di...)
Affinity DataIC50:  7.90E+3nMAssay Description:Inhibition of PAI1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50213737(7-nitro-1,1-dioxo-3-(2-phenoxy-phenylamino)-1,4-di...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of histamine H1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50213737(7-nitro-1,1-dioxo-3-(2-phenoxy-phenylamino)-1,4-di...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of 5HT2C receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50213737(7-nitro-1,1-dioxo-3-(2-phenoxy-phenylamino)-1,4-di...)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of adrenergic beta2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50213737(7-nitro-1,1-dioxo-3-(2-phenoxy-phenylamino)-1,4-di...)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of P38alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50213737(7-nitro-1,1-dioxo-3-(2-phenoxy-phenylamino)-1,4-di...)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of adrenergic A1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50213737(7-nitro-1,1-dioxo-3-(2-phenoxy-phenylamino)-1,4-di...)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of P2Y1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1 adrenergic receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50213737(7-nitro-1,1-dioxo-3-(2-phenoxy-phenylamino)-1,4-di...)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of adrenergic beta-1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50213737(7-nitro-1,1-dioxo-3-(2-phenoxy-phenylamino)-1,4-di...)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of 5HT4A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50213737(7-nitro-1,1-dioxo-3-(2-phenoxy-phenylamino)-1,4-di...)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of adenosine A2a receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50213737(7-nitro-1,1-dioxo-3-(2-phenoxy-phenylamino)-1,4-di...)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of 5HT7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed