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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
14
hits in this display
Target
Sialidase A
(Streptococcus pneumoniae)
Korea Research Institute Of Bioscience And Biotechnology
Curated by
ChEMBL
Ligand
BDBM50182491
(CHEBI:69015 | Malabaricone C)
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Affinity Data
Ki: 100nM
Assay Description:
Competitive inhibition of Streptococcus pneumoniae sialidase NanA using 4-methylumbelliferyl-alpha-D-N-acetylneuraminic acid as substrate after 60 mi...
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Target
Acetylcholinesterase
(Homo sapiens (Human))
University Of Malaya
Curated by
ChEMBL
Ligand
BDBM50182491
(CHEBI:69015 | Malabaricone C)
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Affinity Data
Ki: 5.86E+3nM
Assay Description:
Mixed inhibition of AChE (unknown origin) using acetylthiocholine iodide as substrate incubated for 30 mins by Lineweaver-Burk plot analysis
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Target Info
PDB
MMDB
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KEGG
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Target
Cholinesterase
(Equus caballus (Horse))
University Of Malaya
Curated by
ChEMBL
Ligand
BDBM50182491
(CHEBI:69015 | Malabaricone C)
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Affinity Data
Ki: 1.15E+4nM
Assay Description:
Mixed inhibition of equine serum BChE using S-butyrylthiocholine chloride as substrate incubated for 30 mins by Lineweaver-Burk plot analysis
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Target Info
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Target
Sialidase A
(Streptococcus pneumoniae)
Korea Research Institute Of Bioscience And Biotechnology
Curated by
ChEMBL
Ligand
BDBM50182491
(CHEBI:69015 | Malabaricone C)
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Copy InChI
Affinity Data
IC50: 300nM
Assay Description:
Inhibition of Streptococcus pneumoniae sialidase NanA using 4-methylumbelliferyl-alpha-D-N-acetylneuraminic acid as substrate after 60 mins by FRET a...
More data for this Ligand-Target Pair
Target Info
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UniProtKB/SwissProt
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Article
PubMed
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Target
Phosphatidylcholine:ceramide cholinephosphotransferase 2
(Homo sapiens (Human))
Hokkaido University
Curated by
ChEMBL
Ligand
BDBM50182491
(CHEBI:69015 | Malabaricone C)
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Affinity Data
IC50: 1.00E+3nM
Assay Description:
Noncompetitive inhibition of SMS2 (unknown origin) stably expressed in mouse ZS cells using 5 to 50 uM C6-NBD-ceramide as substrate preincubated for ...
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Target Info
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Target
Phosphatidylcholine:ceramide cholinephosphotransferase 2
(Homo sapiens (Human))
Hokkaido University
Curated by
ChEMBL
Ligand
BDBM50182491
(CHEBI:69015 | Malabaricone C)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.50E+3nM
Assay Description:
Inhibition of SMS2 (unknown origin) stably expressed in mouse ZS cells using C6-NBD-ceramide as substrate preincubated for 30 mins followed by substr...
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
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PC sid
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In Depth
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Article
PubMed
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Target
Acetylcholinesterase
(Homo sapiens (Human))
University Of Malaya
Curated by
ChEMBL
Ligand
BDBM50182491
(CHEBI:69015 | Malabaricone C)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.94E+3nM
Assay Description:
Inhibition of AChE (unknown origin) using acetylthiocholine iodide as substrate incubated for 30 mins by Ellman's microplate assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
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PC sid
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In Depth
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Article
PubMed
Copy BDB DOI
Target
Phosphatidylcholine:ceramide cholinephosphotransferase 1
(Homo sapiens (Human))
Hokkaido University
Curated by
ChEMBL
Ligand
BDBM50182491
(CHEBI:69015 | Malabaricone C)
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Affinity Data
IC50: 2.00E+3nM
Assay Description:
Noncompetitive inhibition of SMS1 (unknown origin) stably expressed in mouse ZS cells using 5 to 50 uM C6-NBD-ceramide as substrate preincubated for ...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
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PC sid
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In Depth
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Article
PubMed
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Target
Cholinesterase
(Equus caballus (Horse))
University Of Malaya
Curated by
ChEMBL
Ligand
BDBM50182491
(CHEBI:69015 | Malabaricone C)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.80E+3nM
Assay Description:
Inhibition of equine serum BChE using S-butyrylthiocholine chloride as substrate incubated for 30 mins by Ellman's microplate assay
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
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PC cid
PC sid
Patents
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In Depth
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Article
PubMed
Copy BDB DOI
Target
Phosphatidylcholine:ceramide cholinephosphotransferase 1
(Homo sapiens (Human))
Hokkaido University
Curated by
ChEMBL
Ligand
BDBM50182491
(CHEBI:69015 | Malabaricone C)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3.00E+3nM
Assay Description:
Inhibition of SMS1 (unknown origin) stably expressed in mouse ZS cells using C6-NBD-ceramide as substrate preincubated for 30 mins followed by substr...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
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PC cid
PC sid
Patents
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In Depth
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Article
PubMed
Copy BDB DOI
Target
Pancreatic alpha-amylase
(Sus scrofa (Pig))
Csir-National Institute For Interdisciplinary Science And Technology
Curated by
ChEMBL
Ligand
BDBM50182491
(CHEBI:69015 | Malabaricone C)
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Affinity Data
IC50: 1.06E+4nM
Assay Description:
Inhibition of porcine pancreatic alpha-amylase using starch as substrate after 30 mins by iodine reagent based assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
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B.MOAD
GoogleScholar
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PC cid
PC sid
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In Depth
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Article
PubMed
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Target
Phosphatidylcholine:ceramide cholinephosphotransferase 2
(Mus musculus)
Hokkaido University
Curated by
ChEMBL
Ligand
BDBM50182491
(CHEBI:69015 | Malabaricone C)
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Affinity Data
IC50: 1.10E+4nM
Assay Description:
Inhibition of SMS2 in MEF cells using C6-NBD-ceramide as substrate preincubated for 1 hr followed by substrate addition and measured after 1 hr by HP...
More data for this Ligand-Target Pair
Target Info
MMDB
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Patents
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In Depth
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Article
PubMed
Copy BDB DOI
Target
Phosphatidylcholine:ceramide cholinephosphotransferase 1
(Mus musculus)
Hokkaido University
Curated by
ChEMBL
Ligand
BDBM50182491
(CHEBI:69015 | Malabaricone C)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.30E+4nM
Assay Description:
Inhibition of SMS1 in MEF cells using C6-NBD-ceramide as substrate preincubated for 1 hr followed by substrate addition and measured after 1 hr by HP...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Albumin
(Bos taurus)
Csir-National Institute For Interdisciplinary Science And Technology
Curated by
ChEMBL
Ligand
BDBM50182491
(CHEBI:69015 | Malabaricone C)
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Affinity Data
IC50: 1.50E+4nM
Assay Description:
Antiglycation activity in bovine serum albumin assessed as inhibition of advanced glycated end product formation after 24 hrs in presence of alpha-D-...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Patents
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In Depth
Details
Article
PubMed
Copy BDB DOI