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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 5 hits in this display   

TargetCytochrome P450 1B1(Homo sapiens (Human))
Showa Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM89011(2-(4-hydroxyphenyl)-4-benzo[h][1]benzopyranone | 2...)
Affinity DataIC50:  43nMAssay Description:Inhibition of human recombinant CYP1B1 using 7-ethoxyresorufin as substrate after 30 mins in presence of NADPH by EROD assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A1(Homo sapiens (Human))
Showa Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM89011(2-(4-hydroxyphenyl)-4-benzo[h][1]benzopyranone | 2...)
Affinity DataIC50:  43nMAssay Description:Inhibition of human recombinant CYP1A1 using 7-ethoxyresorufin as substrate after 15 mins in presence of NADPH by EROD assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Showa Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM89011(2-(4-hydroxyphenyl)-4-benzo[h][1]benzopyranone | 2...)
Affinity DataIC50:  909nMAssay Description:Inhibition of human recombinant CYP1A2 using 7-ethoxyresorufin as substrate after 30 mins in presence of NADPH by EROD assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target26S proteasome non-ATPase regulatory subunit 14(Homo sapiens (Human))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM89011(2-(4-hydroxyphenyl)-4-benzo[h][1]benzopyranone | 2...)
Affinity DataIC50:  4.77E+4nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford Burnham Medical Research Institute (SBMRI, La Jolla, CA...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetProthrombin(Bos taurus (Bovine))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM89011(2-(4-hydroxyphenyl)-4-benzo[h][1]benzopyranone | 2...)
Affinity DataIC50:  6.22E+4nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford Burnham Medical Research Institute (SBMRI, La Jolla, CA...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay