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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 10 hits in this display   

TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Loma Linda University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM26660(3,7-dihydroxy-2-phenyl-4H-chromen-4-one | 3,7-dihy...)
Affinity DataIC50:  4.57E+3nMAssay Description:Inhibition of PIM1 kinaseChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Loma Linda University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM26660(3,7-dihydroxy-2-phenyl-4H-chromen-4-one | 3,7-dihy...)
Affinity DataIC50:  4.60E+3nMpH: 7.0 T: 2°CAssay Description:The 96-well flat-bottomed plates were coated with recombinant GST-BAD. After the plates were blocked, the reaction buffer containing test compound an...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-acyl-carrier protein reductase(Plasmodium falciparum)
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM26660(3,7-dihydroxy-2-phenyl-4H-chromen-4-one | 3,7-dihy...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of FabIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 3(Homo sapiens (Human))
Josip Juraj Strossmayer University of Osijek

LigandPNGBDBM26660(3,7-dihydroxy-2-phenyl-4H-chromen-4-one | 3,7-dihy...)
Affinity DataIC50:  9.80E+4nMpH: 7.4 T: 2°CAssay Description:The inhibitory activity of flavonoids toward human DPP III was assayed in a 50 mM Tris-HCl buffer, pH 7.4. In brief, recombinant human DPP III (0.29 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Homo sapiens (Human))
Universidad De Santiago De Chile

Curated by ChEMBL
LigandPNGBDBM26660(3,7-dihydroxy-2-phenyl-4H-chromen-4-one | 3,7-dihy...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of 12-hLOMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15B(Homo sapiens (Human))
Universidad De Santiago De Chile

Curated by ChEMBL
LigandPNGBDBM26660(3,7-dihydroxy-2-phenyl-4H-chromen-4-one | 3,7-dihy...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of 15-hLO2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Universidad De Santiago De Chile

Curated by ChEMBL
LigandPNGBDBM26660(3,7-dihydroxy-2-phenyl-4H-chromen-4-one | 3,7-dihy...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of 15-hLO1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Institut De Recerca BiomèDica De Barcelona

Curated by ChEMBL
LigandPNGBDBM26660(3,7-dihydroxy-2-phenyl-4H-chromen-4-one | 3,7-dihy...)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of DPP4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl endopeptidase(Homo sapiens (Human))
Institut De Recerca BiomèDica De Barcelona

Curated by ChEMBL
LigandPNGBDBM26660(3,7-dihydroxy-2-phenyl-4H-chromen-4-one | 3,7-dihy...)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of human brain prolyl oligopeptidase expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Central University Of Punjab

Curated by ChEMBL
LigandPNGBDBM26660(3,7-dihydroxy-2-phenyl-4H-chromen-4-one | 3,7-dihy...)
Affinity DataIC50:  1.25E+7nMAssay Description:Inhibition of P-gp in human HK2 cells assessed as Rhodamine-123 accumulation by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed