Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetCytochrome P450 1A1(Homo sapiens (Human))
Gilead Sciences

US Patent

LigandBDBM195591(US9216974,Resorufin | US9333197, Resorufin)Copy SMILESCopy InChI

Affinity DataIC50: >2.50E+4nMAssay Description:Six test compound concentrations (0.1, 0.25, 1, 2.5, 10, 25 μM in DMSO; final DMSO concentration=0.3%) are incubated with human liver microsomes...More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPurchasePC cidPC sidPDB

In DepthDetails US Patent
Copy BDB DOI

TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Washington University

US Patent

LigandBDBM195591(US9216974,Resorufin | US9333197, Resorufin)Copy SMILESCopy InChI

Affinity DataKd:  225nMAssay Description:To determine the Ki values, fixed brain tissues prepared from 15-month-old Tg2576 mice (N=5) will be incubated for 30 min with 1 μM methoxy-X34 ...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPurchasePC cidPC sidPDB

In DepthDetails US Patent
Copy BDB DOI