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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
13
hits in this display
Target
Adenosine receptor A1
(Rattus norvegicus (rat))
National Institute Of Diabetes
Curated by
ChEMBL
Ligand
BDBM50049385
(5-Hydroxy-2-phenyl-chromen-4-one | 5-Hydroxyflavon...)
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Affinity Data
Ki: 2.17E+3nM
Assay Description:
Displacement of specific [3H]-PIA binding from adenosine A1 receptor in rat brain membranes.
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Target
Adenosine receptor A1
(Rattus norvegicus (rat))
National Institute Of Diabetes
Curated by
ChEMBL
Ligand
BDBM50049385
(5-Hydroxy-2-phenyl-chromen-4-one | 5-Hydroxyflavon...)
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Affinity Data
Ki: 2.19E+3nM
Assay Description:
Ability to displace [3H]N6-phenylisopropyladenosine binding from adenosine A1 receptor.
Checked by Author
More data for this Ligand-Target Pair
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Target
Pyruvate kinase PKM
(Homo sapiens (Human))
Central University Of Punjab
Curated by
ChEMBL
Ligand
BDBM50049385
(5-Hydroxy-2-phenyl-chromen-4-one | 5-Hydroxyflavon...)
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Affinity Data
Ki: 3.53E+3nM
Assay Description:
Binding affinity to PKM2 (unknown origin) assessed as oxidation of beta-NADH by spectrophotometry based LDH coupled assay
More data for this Ligand-Target Pair
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Target
Adenosine receptor A2a
(Rattus norvegicus (rat))
National Institute Of Diabetes
Curated by
ChEMBL
Ligand
BDBM50049385
(5-Hydroxy-2-phenyl-chromen-4-one | 5-Hydroxyflavon...)
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Affinity Data
Ki: 6.17E+3nM
Assay Description:
Ability to displace [3H]-CGS- 21680 binding from adenosine A2A receptor.
Checked by Author
More data for this Ligand-Target Pair
Target Info
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Target
Adenosine receptor A2a
(Rattus norvegicus (rat))
National Institute Of Diabetes
Curated by
ChEMBL
Ligand
BDBM50049385
(5-Hydroxy-2-phenyl-chromen-4-one | 5-Hydroxyflavon...)
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Affinity Data
Ki: 6.20E+3nM
Assay Description:
Affinity at Adenosine A2A receptor in rat striatal membranes by [3H]- CGS 21680 displacement.
More data for this Ligand-Target Pair
Target Info
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Target
Cytochrome P450 1B1
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM50049385
(5-Hydroxy-2-phenyl-chromen-4-one | 5-Hydroxyflavon...)
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Affinity Data
IC50: 210nM
Assay Description:
Inhibition of human CYP1B1 expressed in Escherichia coli DH5alpha coexpressing human NADPH P450 reductase using 7-ethoxyresorufin as substrate in pre...
More data for this Ligand-Target Pair
Target Info
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Target
Androgen receptor
(Homo sapiens (Human))
Meijo University
Curated by
ChEMBL
Ligand
BDBM50049385
(5-Hydroxy-2-phenyl-chromen-4-one | 5-Hydroxyflavon...)
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Affinity Data
IC50: 300nM
Assay Description:
Antagonist activity at androgen receptor in human MDA-kb2 cells assessed as inhibition of DHT-induced luciferase activity by luciferase reporter gene...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
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Target
Cytochrome P450 1A2
(Homo sapiens (Human))
Xavier University Of Louisiana
Curated by
ChEMBL
Ligand
BDBM50049385
(5-Hydroxy-2-phenyl-chromen-4-one | 5-Hydroxyflavon...)
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Affinity Data
IC50: 310nM
Assay Description:
Inhibition of CYP1A2 (unknown origin)-mediated demethylation of resorufin methyl ether after 5 mins by spectrofluorimetric analysis
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
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Target
Androgen receptor
(Homo sapiens (Human))
Meijo University
Curated by
ChEMBL
Ligand
BDBM50049385
(5-Hydroxy-2-phenyl-chromen-4-one | 5-Hydroxyflavon...)
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Affinity Data
IC50: 832nM
Assay Description:
Antagonist activity at human androgen receptor LBD expressed in human MDA-kb2 cells by luciferase reporter gene assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
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CHEMBL
PC cid
PC sid
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In Depth
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Article
PubMed
Copy BDB DOI
Target
Androgen receptor
(Homo sapiens (Human))
Meijo University
Curated by
ChEMBL
Ligand
BDBM50049385
(5-Hydroxy-2-phenyl-chromen-4-one | 5-Hydroxyflavon...)
Copy SMILES
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Affinity Data
IC50: 840nM
Assay Description:
Antagonist activity at human androgen receptor LBD expressed in human MDA-kb2 cells by luciferase reporter gene assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
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CHEMBL
PC cid
PC sid
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In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Pyruvate kinase PKM
(Homo sapiens (Human))
Central University Of Punjab
Curated by
ChEMBL
Ligand
BDBM50049385
(5-Hydroxy-2-phenyl-chromen-4-one | 5-Hydroxyflavon...)
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Affinity Data
IC50: 1.39E+3nM
Assay Description:
Inhibition of recombinant PKM2 (unknown origin) Thr129, Ser205, Hie78, Lys367, Ala366, Gly52 residues
More data for this Ligand-Target Pair
Target Info
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Target
Cytochrome P450 1A1
(Homo sapiens (Human))
Xavier University Of Louisiana
Curated by
ChEMBL
Ligand
BDBM50049385
(5-Hydroxy-2-phenyl-chromen-4-one | 5-Hydroxyflavon...)
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Affinity Data
IC50: 4.03E+3nM
Assay Description:
Inhibition of CYP1A1 (unknown origin)-mediated deethylation of resorufin ethyl ether after 5 mins by spectrofluorimetric analysis
More data for this Ligand-Target Pair
Target Info
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Target
Sialidase-2
(Homo sapiens (Human))
Hokkaido University
Curated by
ChEMBL
Ligand
BDBM50049385
(5-Hydroxy-2-phenyl-chromen-4-one | 5-Hydroxyflavon...)
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Affinity Data
IC50: >1.00E+6nM
Assay Description:
Inhibition of human Neu2 assessed as MuNANA substrate hydrolysis in presence of 0.1% Triton X-100 by discontinuous fluorimetric assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
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Ligand Info
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CHEMBL
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PC sid
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PubMed
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