Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetCathepsin G(Homo sapiens (Human))
Suntory

Curated by ChEMBL

LigandBDBM50058992(3-(4-Chloro-benzenesulfonyl)-1-pyridin-2-yl-imidaz...)Copy SMILESCopy InChI

Affinity DataIC50:  8.50E+3nMAssay Description:Inhibitory activity against human neutrophil cathepsin G.More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetChymase(Homo sapiens (Human))
Suntory

Curated by ChEMBL

LigandBDBM50058992(3-(4-Chloro-benzenesulfonyl)-1-pyridin-2-yl-imidaz...)Copy SMILESCopy InChI

Affinity DataIC50:  1.80E+4nMAssay Description:Inhibitory activity against human heart chymase in vitro.More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetChymotrypsinogen A(Bos taurus (bovine))
Suntory

Curated by ChEMBL

LigandBDBM50058992(3-(4-Chloro-benzenesulfonyl)-1-pyridin-2-yl-imidaz...)Copy SMILESCopy InChI

Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory activity against bovine pancreas alpha-chymotrypsin in vitroMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankGoogleScholar

Ligand InfoCHEMBLPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI