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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
8
hits in this display
Target
Histone deacetylase 6
(Homo sapiens (Human))
R&D Sigma-Tau Industrie Farmaceutiche Riunite
Curated by
ChEMBL
Ligand
BDBM50027601
(8-Mercapto-Octanoic Acid Phenylamide)
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Affinity Data
IC50: 70nM
Assay Description:
Inhibition of HDAC6 (unknown origin) using fluorogenic tetrapeptide RHKK(Ac) substrate by fluorescence assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histone deacetylase 3
(Homo sapiens (Human))
R&D Sigma-Tau Industrie Farmaceutiche Riunite
Curated by
ChEMBL
Ligand
BDBM50027601
(8-Mercapto-Octanoic Acid Phenylamide)
Copy SMILES
Copy InChI
Affinity Data
IC50: 110nM
Assay Description:
Inhibition of HDAC3 (unknown origin) using fluorogenic tetrapeptide RHKK(Ac) substrate by fluorescence assay
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histone deacetylase 11
(Homo sapiens (Human))
R&D Sigma-Tau Industrie Farmaceutiche Riunite
Curated by
ChEMBL
Ligand
BDBM50027601
(8-Mercapto-Octanoic Acid Phenylamide)
Copy SMILES
Copy InChI
Affinity Data
IC50: 133nM
Assay Description:
Inhibition of HDAC11 (unknown origin) using fluorogenic tetrapeptide RHKK(Ac) substrate by fluorescence assay
More data for this Ligand-Target Pair
Target Info
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Polyamine deacetylase HDAC10
(Homo sapiens (Human))
R&D Sigma-Tau Industrie Farmaceutiche Riunite
Curated by
ChEMBL
Ligand
BDBM50027601
(8-Mercapto-Octanoic Acid Phenylamide)
Copy SMILES
Copy InChI
Affinity Data
IC50: 252nM
Assay Description:
Inhibition of HDAC10 (unknown origin) using fluorogenic tetrapeptide RHKK(Ac) substrate by fluorescence assay
More data for this Ligand-Target Pair
Target Info
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histone deacetylase 1
(Homo sapiens (Human))
R&D Sigma-Tau Industrie Farmaceutiche Riunite
Curated by
ChEMBL
Ligand
BDBM50027601
(8-Mercapto-Octanoic Acid Phenylamide)
Copy SMILES
Copy InChI
Affinity Data
IC50: 294nM
Assay Description:
Inhibition of HDAC1 (unknown origin) using fluorogenic tetrapeptide RHKK(Ac) substrate by fluorescence assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histone deacetylase 2
(Homo sapiens (Human))
R&D Sigma-Tau Industrie Farmaceutiche Riunite
Curated by
ChEMBL
Ligand
BDBM50027601
(8-Mercapto-Octanoic Acid Phenylamide)
Copy SMILES
Copy InChI
Affinity Data
IC50: 754nM
Assay Description:
Inhibition of HDAC2 (unknown origin) using fluorogenic tetrapeptide RHKK(Ac) substrate by fluorescence assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histone deacetylase 8
(Homo sapiens (Human))
R&D Sigma-Tau Industrie Farmaceutiche Riunite
Curated by
ChEMBL
Ligand
BDBM50027601
(8-Mercapto-Octanoic Acid Phenylamide)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.12E+3nM
Assay Description:
Inhibition of HDAC8 (unknown origin) using fluorogenic tetrapeptide RHK(Ac)K(Ac) substrate by fluorescence assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histone deacetylase
(Homo sapiens (Human))
Nagoya City University
Curated by
ChEMBL
Ligand
BDBM50027601
(8-Mercapto-Octanoic Acid Phenylamide)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.50E+3nM
Assay Description:
Inhibitory concentration against human histone deacetylase
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI