Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetProteasome subunit beta type-8(Homo sapiens (Human))
Hungarian Academy Of Sciences

Curated by ChEMBL

LigandBDBM50570899(2-Mercaptobenzimidazole)Copy SMILESCopy InChI

Affinity DataIC50:  1.14E+5nMAssay Description:Inhibition of human chymotrypsin-like beta 5i subunit of iCP using suc-LLVY-AMC as flurogenic substrate for 90 mins by fluorescence-based assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetGlutaminyl-peptide cyclotransferase(Homo sapiens (Human))
Ewha Womans University

Curated by ChEMBL

LigandBDBM50570899(2-Mercaptobenzimidazole)Copy SMILESCopy InChI

Affinity DataIC50:  5.51E+5nMAssay Description:Inhibition of recombinant human QC using H-Gln-AMC hydrobromide as fluorogenic substrate incubated for 6 hrs by fluorometric microplate reader analys...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails PubMed
Copy BDB DOI