Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetAspartyl/asparaginyl beta-hydroxylase(Human)
University of Oxford

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50627748BDBM50627748(CHEMBL5429166)
Affinity DataIC50: 1.22E+3nMAssay Description:Inhibition of N-terminal his6-tagged human recombinant AspH (315 to 758 residues) expressed in Escherichia coli BL21 (DE3) cells by SPE-MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetLysine-specific demethylase 4E(Human)
University of Oxford

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50627748BDBM50627748(CHEMBL5429166)
Affinity DataIC50: 3.69E+3nMAssay Description:Inhibition of human recombinant KDM4E using biotinylated-H3K9me3 peptide as substrate by SPE-MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetBifunctional peptidase and arginyl-hydroxylase JMJD5(Homo sapiens)
University of Oxford

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50627748BDBM50627748(CHEMBL5429166)
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of N-terminal his6-tagged human recombinant JMJD5 (183 to 416 residues) using RPS6 as substrate by SPE-MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed