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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kJ/mol
)
Found
3
hits in this display
Target
NACHT, LRR and PYD domains-containing protein 3
(Homo sapiens (Human))
Nodthera
Curated by
ChEMBL
Ligand
BDBM50553945
(CHEMBL4790034)
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Affinity Data
IC50: 30nM
Assay Description:
Inhibition of NLRP3 in human PBMC cells assessed as inhibition of LPS and ATP-induced IL-1beta production
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
NACHT, LRR and PYD domains-containing protein 3
(Homo sapiens (Human))
Nodthera
Curated by
ChEMBL
Ligand
BDBM50553945
(CHEMBL4790034)
Copy SMILES
Copy InChI
Affinity Data
IC50: 200nM
Assay Description:
Inhibition of NLRP3 in human THP-1 cells assessed as reduction in nigercin-induced ASC speck formation measuring green fluorescent protein aggregatio...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
NACHT, LRR and PYD domains-containing protein 3
(Homo sapiens (Human))
Nodthera
Curated by
ChEMBL
Ligand
BDBM50553945
(CHEMBL4790034)
Copy SMILES
Copy InChI
Affinity Data
IC50: 370nM
Assay Description:
Inhibition of NLRP3 in human whole blood assessed as inhibition of LPS and ATP-induced IL-1beta production
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI