Report error Found 19 Enz. Inhib. hit(s) with Target = 'Inositol 1,4,5-trisphosphate receptor type 3'
Affinity DataKi: 26.4nMAssay Description:Compound was evaluated for its ability to displace [3H]Ins(1,4,5)P3 from membranes prepared from bovine adrenal corticlesMore data for this Ligand-Target Pair
TargetInositol 1,4,5-trisphosphate receptor type 3(Human)
Bergische UniversitäT Wuppertal
Curated by ChEMBL
Bergische UniversitäT Wuppertal
Curated by ChEMBL
Affinity DataIC50: 2.90nMAssay Description:Inhibition of Ins(1,3,4,5)P4-PtdIns(3,4,5)P3-specific receptor from Pig cerebellum membraneMore data for this Ligand-Target Pair
TargetInositol 1,4,5-trisphosphate receptor type 3(Human)
Bergische UniversitäT Wuppertal
Curated by ChEMBL
Bergische UniversitäT Wuppertal
Curated by ChEMBL
Affinity DataIC50: 6.10nMAssay Description:Inhibition of Ins(1,3,4,5)P4-PtdIns(3,4,5)P3-specific receptor from Pig cerebellum membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Binding affinity towards Inositol 1,4,5-trisphosphate receptor was evaluated by the standard competitive binding assay using 1.25 nM [3H]-D-I(1,4,5)P...More data for this Ligand-Target Pair
TargetInositol 1,4,5-trisphosphate receptor type 3(Human)
Bergische UniversitäT Wuppertal
Curated by ChEMBL
Bergische UniversitäT Wuppertal
Curated by ChEMBL
Affinity DataIC50: 44nMAssay Description:Inhibition of Ins(1,3,4,5)P4-PtdIns(3,4,5)P3-specific receptor from Pig cerebellum membraneMore data for this Ligand-Target Pair
TargetInositol 1,4,5-trisphosphate receptor type 3(Human)
Bergische UniversitäT Wuppertal
Curated by ChEMBL
Bergische UniversitäT Wuppertal
Curated by ChEMBL
Affinity DataIC50: 430nMAssay Description:Inhibition of Ins(1,3,4,5)P4-PtdIns(3,4,5)P3-specific receptor from Pig cerebellum membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 598nMAssay Description:Binding affinity towards Inositol 1,4,5-trisphosphate receptor was evaluated by the standard competitive binding assay using 1.25 nM [3H]-D-I(1,4,5)P...More data for this Ligand-Target Pair
TargetInositol 1,4,5-trisphosphate receptor type 3(Human)
Bergische UniversitäT Wuppertal
Curated by ChEMBL
Bergische UniversitäT Wuppertal
Curated by ChEMBL
Affinity DataIC50: 620nMAssay Description:Inhibition of Ins(1,3,4,5)P4-PtdIns(3,4,5)P3-specific receptor from Pig cerebellum membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity against Inositol 1,4,5-trisphosphate receptor on bovine adrenal cortex microsomes.More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Binding affinity against Inositol 1,4,5-trisphosphate receptor on bovine adrenal cortex microsomes.More data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+3nMAssay Description:Binding affinity against Inositol 1,4,5-trisphosphate receptor on bovine adrenal cortex microsomes.More data for this Ligand-Target Pair
Affinity DataIC50: 3.90E+3nMAssay Description:Binding affinity against Inositol 1,4,5-trisphosphate receptor on bovine adrenal cortex microsomes.More data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMAssay Description:Binding affinity against Inositol 1,4,5-trisphosphate receptor on bovine adrenal cortex microsomes.More data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+4nMAssay Description:Binding affinity against Inositol 1,4,5-trisphosphate receptor on bovine adrenal cortex microsomes.More data for this Ligand-Target Pair
TargetInositol 1,4,5-trisphosphate receptor type 3(Human)
Bergische UniversitäT Wuppertal
Curated by ChEMBL
Bergische UniversitäT Wuppertal
Curated by ChEMBL
Affinity DataEC50: 210nMAssay Description:Compound was evaluated for its effective dose to inhibit the calcium release as a measure of affinity for Ins(1,4,5)P3 receptorMore data for this Ligand-Target Pair
TargetInositol 1,4,5-trisphosphate receptor type 3(Human)
Bergische UniversitäT Wuppertal
Curated by ChEMBL
Bergische UniversitäT Wuppertal
Curated by ChEMBL
Affinity DataKd: 188nMpH: 7.4Assay Description:Dissociation constant of compound was measured in IP3-binding domain(IBD) of human Inositol 1,4,5-trisphosphate receptor at pH 7.4More data for this Ligand-Target Pair
TargetInositol 1,4,5-trisphosphate receptor type 3(Human)
Bergische UniversitäT Wuppertal
Curated by ChEMBL
Bergische UniversitäT Wuppertal
Curated by ChEMBL
Affinity DataKd: 1.12E+3nMpH: 7.4Assay Description:Dissociation constant of compound was measured in IP3-binding domain(IBD) of human Inositol 1,4,5-trisphosphate receptor at pH 7.4More data for this Ligand-Target Pair
TargetInositol 1,4,5-trisphosphate receptor type 3(Human)
Bergische UniversitäT Wuppertal
Curated by ChEMBL
Bergische UniversitäT Wuppertal
Curated by ChEMBL
Affinity DataKd: 1.20nMpH: 7.4Assay Description:Dissociation constant of compound was measured in IP3-binding domain(IBD) of human Inositol 1,4,5-trisphosphate receptor at pH 7.4More data for this Ligand-Target Pair
TargetInositol 1,4,5-trisphosphate receptor type 3(Human)
Bergische UniversitäT Wuppertal
Curated by ChEMBL
Bergische UniversitäT Wuppertal
Curated by ChEMBL
Affinity DataKd: 195nMpH: 7.4Assay Description:Dissociation constant of compound was measured in IP3-binding domain(IBD) of human Inositol 1,4,5-trisphosphate receptor at pH 7.4More data for this Ligand-Target Pair