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Query String: LAMIVUDINE

BMS-205603-01 Lamivudine impurity e SQ-7726 NSC-3970 BDBM50549809 CHEBI:17568 Fluorouracil specified compound c Hybar x SQ-8493 Lamivudine impurity e rs SQ-6201 Uracil Pyrod
LAMIVUDINE [(2R,5S)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-1,3-oxathiolan-2-yl]methyl tetrahydrogen triphosphate 3TC Triphosphate [[[5-(4-amino-2-oxo-1H-pyrimidin-1-yl)-1,3-oxathiolan-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxyphosphonic acid Lamivudine triphosphate CHEMBL1230 BDBM50138406

Zelina, S; Sheen, CW; Radzio, J; Mellors, JW; Sluis-Cremer, N Mechanisms by which the G333D mutation in human immunodeficiency virus type 1 Reverse transcriptase facilitates dual resistance to zidovudine and lamivudine. Antimicrob Agents Chemother 52: 157-63 (2008)

ChEMBL_1743357 (CHEMBL4177867) Inhibition of lamivudine-resistant wild type hepatitis B virus capsid assembly in human Huh7 cells assessed as reduction in intracellular DNA levels measured on day 7 by real-time PCR analysis
ChEMBL_1743361 (CHEMBL4177871) Inhibition of lamivudine-resistant wild type hepatitis B virus capsid assembly in human Huh7 cells assessed as reduction in secreted DNA levels measured on day 7 by real-time PCR analysis
ChEMBL_1743358 (CHEMBL4177868) Inhibition of reverse transcriptase M204I mutant expressing lamivudine-resistant hepatitis B virus capsid assembly in human Huh7 cells assessed as reduction in intracellular DNA levels measured on day 7 by real-time PCR analysis
ChEMBL_1743360 (CHEMBL4177870) Inhibition of reverse transcriptase M204I mutant expressing lamivudine-resistant hepatitis B virus capsid assembly in human Huh7 cells assessed as reduction in secreted DNA levels measured on day 7 by real-time PCR analysis
ChEMBL_1852283 (CHEMBL4352907) Inhibition of capsid protein in lamivudine/entecavir-resistant Hepatitis B virus harboring rtL180M/rtM204V/rt184L mutant infected in human HepG2.2.15 cells assessed as reduction in viral DNA level measured after 72 hrs by PCR analysis
ChEMBL_1743359 (CHEMBL4177869) Inhibition of reverse transcriptase M204I/V173L double mutant expressing lamivudine-resistant hepatitis B virus capsid assembly in human Huh7 cells assessed as reduction in secreted DNA levels measured on day 7 by real-time PCR analysis
ChEMBL_1743362 (CHEMBL4177872) Inhibition of reverse transcriptase M204I/VI73L double mutant expressing lamivudine-resistant hepatitis B virus capsid assembly in human Huh7 cells assessed as reduction in intracellular DNA levels measured on day 7 by real-time PCR analysis