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Found 8 of ec50 for monomerid = 50453114
TargetGenome polyprotein(Hepatitis C virus (HCV))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50453114(CHEMBL4211348)
Affinity DataEC50:  0.0120nMAssay Description:Inhibition of HCV genotype 1b Con1 NS5A expressed in HuH7 cell infected HCV genotype 2b assessed as decrease in viral replication after 3 days by luc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus (HCV))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50453114(CHEMBL4211348)
Affinity DataEC50:  0.0120nMAssay Description:Inhibition of NS5A in HuH7 cell infected HCV genotype 1b Con1 assessed as decrease in viral replication after 3 days by luciferase reporter gene assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus (HCV))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50453114(CHEMBL4211348)
Affinity DataEC50:  0.0130nMAssay Description:Inhibition of HCV genotype 1b Con1 NS5A expressed in HuH7 cell infected HCV genotype 4a assessed as decrease in viral replication after 3 days by luc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus (HCV))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50453114(CHEMBL4211348)
Affinity DataEC50:  0.0180nMAssay Description:Inhibition of HCV genotype 1b Con1 NS5A expressed in HuH7 cell infected HCV genotype 3a assessed as decrease in viral replication after 3 days by luc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNonstructural protein 5A(Hepatitis C virus)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50453114(CHEMBL4211348)
Affinity DataEC50:  0.0190nMAssay Description:Inhibition of NS5A in HuH7 cell infected HCV genotype 1a H77 assessed as decrease in viral replication after 3 days by luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus (HCV))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50453114(CHEMBL4211348)
Affinity DataEC50:  0.0430nMAssay Description:Inhibition of HCV genotype 1b Con1 NS5A expressed in HuH7 cell infected HCV genotype 2a assessed as decrease in viral replication after 3 days by luc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus (HCV))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50453114(CHEMBL4211348)
Affinity DataEC50:  0.230nMAssay Description:Inhibition of NS5A in HuH7 cell infected HCV genotype 1b Con1 assessed as decrease in viral replication after 3 days in presence of 40% human plasma ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNonstructural protein 5A(Hepatitis C virus)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50453114(CHEMBL4211348)
Affinity DataEC50:  0.276nMAssay Description:Inhibition of NS5A in HuH7 cell infected HCV genotype 1a H77 assessed as decrease in viral replication after 3 days in presence of 40% human plasma b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed