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Found 5 of ic50 for monomerid = 104718
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM104718(US8569308, 138 | US8569308, 220)
Affinity DataIC50:  233nMAssay Description:The mGluR5 activity was determined using the metabotropic glutamate receptor activity assays in human embryonic kidney cell.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Vanderbilt University

US Patent
LigandPNGBDBM104718(US8569308, 138 | US8569308, 220)
Affinity DataIC50:  233nMAssay Description:The mGluR5 activity was determined using the metabotropic glutamate receptor activity assays in human embryonic kidney cell.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM104718(US8569308, 138 | US8569308, 220)
Affinity DataIC50:  277nMAssay Description:The mGluR5 activity was determined using the metabotropic glutamate receptor activity assays in human embryonic kidney cell.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Vanderbilt University

US Patent
LigandPNGBDBM104718(US8569308, 138 | US8569308, 220)
Affinity DataIC50:  403nMAssay Description:Negative allosteric modulator activity at rat mGlu5 expressed in HEK293A cells assessed as reduction in glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Vanderbilt University

US Patent
LigandPNGBDBM104718(US8569308, 138 | US8569308, 220)
Affinity DataIC50:  407nMAssay Description:Negative allosteric modulator activity at rat mGlu5 expressed in HEK293A cells assessed as reduction in glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed