Compile Data Set for Download or QSAR
maximum 50k data
Found 8 of ic50 for monomerid = 33396
TargetDihydrofolate reductase(Mus musculus (Mouse))
Duquesne University

LigandPNGBDBM33396(2,4-diaminofuro[2,3-d]pyrimidine, 2 | E/Z ratio=2:...)
Affinity DataIC50:  7.92E+3nMAssay Description:Standard DHFR assays were conducted at 37 deg C with continuous recording of change of OD at 340 nm. All determinations of IC50 were made by fitting ...More data for this Ligand-Target Pair
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TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

LigandPNGBDBM33396(2,4-diaminofuro[2,3-d]pyrimidine, 2 | E/Z ratio=2:...)
Affinity DataIC50:  1.18E+4nMAssay Description:Standard DHFR assays were conducted at 37 deg C with continuous recording of change of OD at 340 nm. All determinations of IC50 were made by fitting ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Duquesne University

LigandPNGBDBM33396(2,4-diaminofuro[2,3-d]pyrimidine, 2 | E/Z ratio=2:...)
Affinity DataIC50:  1.22E+4nMAssay Description:Standard DHFR assays were conducted at 37 deg C with continuous recording of change of OD at 340 nm. All determinations of IC50 were made by fitting ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Duquesne University

LigandPNGBDBM33396(2,4-diaminofuro[2,3-d]pyrimidine, 2 | E/Z ratio=2:...)
Affinity DataIC50:  1.52E+4nMAssay Description:Standard DHFR assays were conducted at 37 deg C with continuous recording of change of OD at 340 nm. All determinations of IC50 were made by fitting ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Duquesne University

LigandPNGBDBM33396(2,4-diaminofuro[2,3-d]pyrimidine, 2 | E/Z ratio=2:...)
Affinity DataIC50:  1.78E+4nMAssay Description:Cells used were tumor cell lines naturally expressing high levels of tyrosine kinases. Expression levels at the RNA level were derived from the NCI D...More data for this Ligand-Target Pair
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TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

LigandPNGBDBM33396(2,4-diaminofuro[2,3-d]pyrimidine, 2 | E/Z ratio=2:...)
Affinity DataIC50:  3.70E+4nMAssay Description:Standard DHFR assays were conducted at 37 deg C with continuous recording of change of OD at 340 nm. All determinations of IC50 were made by fitting ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Duquesne University

LigandPNGBDBM33396(2,4-diaminofuro[2,3-d]pyrimidine, 2 | E/Z ratio=2:...)
Affinity DataIC50:  8.82E+4nMpH: 7.4 T: 2°CAssay Description:Cells used were tumor cell lines naturally expressing high levels of tyrosine kinases. Expression levels at the RNA level were derived from the NCI D...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Duquesne University

LigandPNGBDBM33396(2,4-diaminofuro[2,3-d]pyrimidine, 2 | E/Z ratio=2:...)
Affinity DataIC50:  1.60E+5nMpH: 7.4 T: 2°CAssay Description:Cells used were tumor cell lines naturally expressing high levels of tyrosine kinases. Expression levels at the RNA level were derived from the NCI D...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed