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Found 4 of ic50 for monomerid = 405271
TargetG_PROTEIN_RECEP_F1_2 domain-containing protein(Oryctolagus cuniculus (Rabbit))
Shanghai Hengrui Pharmaceutical

US Patent
LigandPNGBDBM405271(1-(4-(3-((dimethylamino)methyl)-5-(2-fluoro-3-meth...)
Affinity DataIC50:  0.270nMAssay Description:Rabbit: This assay was used to determine the inhibition effect of the present compounds on the activity of rabbit GnRHr protein expressed by rabbit G...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGonadotropin-releasing hormone receptor(Rabbit)
Shanghai Hengrui Pharmaceutical

US Patent
LigandPNGBDBM405271(1-(4-(3-((dimethylamino)methyl)-5-(2-fluoro-3-meth...)
Affinity DataIC50:  0.270nMAssay Description:In vitro GnRHr protein activity was tested by the following methods.This assay was used to determine the inhibition effect of the present compound on...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Shanghai Hengrui Pharmaceutical

US Patent
LigandPNGBDBM405271(1-(4-(3-((dimethylamino)methyl)-5-(2-fluoro-3-meth...)
Affinity DataIC50:  0.600nMAssay Description:In vitro GnRHr protein activity was tested by the following methods.This assay was used to determine the inhibition effect of the present compound on...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Shanghai Hengrui Pharmaceutical

US Patent
LigandPNGBDBM405271(1-(4-(3-((dimethylamino)methyl)-5-(2-fluoro-3-meth...)
Affinity DataIC50:  0.600nMAssay Description:Human: Test Example 1. Human GnRHr (GnRH Receptor) Activity Assay of the Present Compounds.In vitro GnRHr protein activity was tested by the followin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent