Found 4 of ic50 for monomerid = 426135 
Affinity DataIC50: 0.0800nMAssay Description:This assay was used to test compounds for their ability to inhibit TARP γ8 dependent AMPA receptor activity. The AMPA receptor is a non-selectiv...More data for this Ligand-Target Pair
TargetGlutamate receptor 1/Voltage-dependent calcium channel gamma-2 subunit(Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Affinity DataIC50: 0.100nMAssay Description:Negative allosteric modulation of recombinant human GluA1 flop isoform/TARPgamma2 expressed in HEK293 cells assessed as inhibition of glutamate-induc...More data for this Ligand-Target Pair
TargetGlutamate receptor 1/Voltage-dependent calcium channel gamma-2 subunit(Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Affinity DataIC50: 0.100nMAssay Description:Negative allosteric modulation of recombinant human GluA1 flop isoform/TARPgamma2 expressed in HEK293 cells assessed as inhibition of glutamate-induc...More data for this Ligand-Target Pair
TargetVoltage-dependent calcium channel gamma-8 subunit(Rattus norvegicus)
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Affinity DataIC50: <1.00E+4nMAssay Description:Negative allosteric modulation of TARPgamma8 in rat hippocampal neurons assessed as inhibition of glutamate-induced current at 10 uM at -60 mV holdin...More data for this Ligand-Target Pair
